Results 81 to 90 of about 9,811,178 (296)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Attenuation of offset analgesia is associated with suppression of descending pain modulatory and reward systems in patients with chronic pain

open access: yesMolecular Pain, 2018
Background Offset analgesia is a disproportionate decrease of pain perception following a slight decrease of noxious thermal stimulus and attenuated in patients with neuropathic pain.
Shuo Zhang   +5 more
doaj   +1 more source

Linear Offset-Free Model Predictive Control in the Dynamic PLS Framework

open access: yesInformation, 2018
This work addresses the model predictive control (MPC) of the offset-free tracking problem in the dynamic partial least square (DyPLS) framework. Firstly, state space MPC based on the DyPLS is proposed.
Ligang Hou, Ze Wu, Xin Jin, Yue Wang
doaj   +1 more source

Offset-free control of constrained linear discrete-time systems subject to persistent unmeasured disturbances [PDF]

open access: yes, 2003
This paper addresses the design of a dynamic, nonlinear, time-invariant, state feedback controller that guarantees constraint satisfaction and offset-free control in the presence of unmeasured, persistent, non-stationary, additive disturbances.
PANNOCCHIA, GABRIELE   +5 more
core   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

GNSS Navigation Spoofing Method of UAV Based on Point-by-point Offset

open access: yes工程科学与技术, 2023
Aiming at the harm of UAVs in the aspects of out-of-control accident and air traffic control interference, a GNSS navigation spoofing method based on point-by-point offset was proposed in this paper, which decoys target UAV to fly away from sensitive ...
Yan GUO, Kanghua TANG, Lu ZHANG
doaj  

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

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