Results 271 to 280 of about 911,118 (353)

Single‐Cell Level Characterization of B Cell Depletion and Repopulation Following Rituximab in Systemic Lupus Erythematosus

Arthritis &Rheumatology, EarlyView.
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang, Norzawani Buang, Catherine Sutherland, Wanseon Lee, Lauren Overend, Tarran S. Rupall, Katie L. Burnham, Matthew C. Pickering, Marina Botto, Emma E. Davenport   +9 more
wiley   +1 more source

Impact of Maternal Lifetime Stress on Offspring Biological Aging: A Systematic Review and Meta-Analysis of Observational Studies. [PDF]

Int J Mol Sci
Muñoz Venegas ML, Quiccione MS, Sharma S, Gianfagna F, Bracone F, De Domenico P, Tirozzi A, Cerletti C, Donati MB, de Gaetano G, Iacoviello L, Gialluisi A.   +11 more
europepmc   +1 more source

Kidney Hematopoietic Stem and Progenitor Cells Contribute to Myeloid Development and Pathology in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective The hematopoietic system maintains homeostasis by balancing myeloid and lymphoid cell production in the bone marrow (BM). In response to increased hematopoietic demand, extramedullary hematopoiesis (EMH) may occur in nonlymphoid organs. We investigated the role of EMH and kidney‐resident hematopoietic stem and progenitor cells (HSPCs) in ...
Hansol Yi, Seyoung Jung, Jeong Ho Joo, Young‐Eun Kim, Heounjeong Go, Yong‐Gil Kim, Chang‐Keun Lee, Bin Yoo, Jeong Seok Lee, Seokchan Hong   +9 more
wiley   +1 more source

The association between prenatal exposure to mixed air pollutants and birth defects risk: a population-based study in Tangshan, China. [PDF]

Front Public Health
Guo M, Li Y, Li H, Yang Y, Zhang H.
europepmc   +1 more source

T cell plasticity in systemic lupus erythematosus revealed by large‐scale T cell receptor repertoire and transcriptome studies

Arthritis &Rheumatology, Accepted Article.
Objective We aimed to characterize CD4+ T cell plasticity in human SLE by leveraging TCR repertoire features as markers of prior lineage states, integrating TCR and transcriptomic profiling to delineate plasticity patterns and evaluate their association with clinical disease activity.
Yasuo Nagafuchi, Masahiro Nakano, Kaitlyn A. Lagattuta, Mineto Ota, Hiroaki Hatano, Haruka Takahashi, Takahiro Itamiya, Hajime Inokuchi, Soumya Raychaudhuri, Tomohisa Okamura, Keishi Fujio, Kazuyoshi Ishigaki   +11 more
wiley   +1 more source

Cross-Generational Integration of Exercise and Nutritional Encoding in Offspring Adipose Genomics. [PDF]

Int J Mol Sci
Chae SA, Yoo C, Son JS.
europepmc   +1 more source

Parent-offspring regression

, 2019
Suzanne Lommen, Peter de Jong, Paul Brakefield, Bardo Cornelder   +3 more
openalex   +1 more source

Labor Epidural Analgesia and Autism Spectrum Disorder in Offspring: A Population‐Based Case–Control Study

Autism Research, EarlyView.
ABSTRACT While the immediate benefits of labor epidural analgesia (LEA) are well established, recent studies have raised concerns about possible associations with autism spectrum disorder (ASD). Therefore, we examined the association between LEA and ASD in offspring.
Taniqua T. Ingol, Jessie K. Edwards, Mollie E. Wood, Chantel L. Martin, Gabriel S. Dichter, Keith Feldman, Alan C. Kinlaw, Julie L. Daniels   +7 more
wiley   +1 more source

Maternal smoking based on pre-birth health examination and risk of neurodevelopmental disorders in offspring: insights from a Korean mother-child cohort. [PDF]

BMC Med
Park CS, Jang M, Kim B, Kwak S, Rhee TM, Lee H, Kim HK, Kim YJ, Kim JW, Han K, Park JB.   +10 more
europepmc   +1 more source