Study to Establish the Relationship between Rabeprazole (PPI) and Acute Interstitial Nephritis (AIN)
Introduction: Proton pump inhibitors (PPIs) are the most commonly used drug worldwide. PPIs are benzimidazole derivatives and are basic in nature; therefore, they are dispensed in enteric-coated tablets or capsules to avoid degradation from gastric acid.
Bite Bapurao +2 more
doaj +1 more source
Evaluation of various methods of susceptibility to ofloxacin in strains of Mycobacterium tuberculosis [PDF]
A comparison of three methods of susceptibility testing was undertaken on 30 susceptible and 25 resistant strains of Mycobacterium tuberculosis to determine an acceptable in vitro definition of resistance of ofloxacin.
Paramasivan, C N +2 more
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Development and validation of high-perfomance liquid chromatographic method for determination of ofloxacin and lomefloxacin in human plasma [PDF]
Ahigh-performance liquid chromatographicmethod for the determination of ofloxacin and lomefloxacin in human plasma has been developed and validated. The effect of organic modifiers on the retention of the investigated drugs was investigated.
DRAGICA ZENDELOVSKA, TRAJCE STAFILOV
doaj
Simple spectrofluorimetric and microbiological assay methods for the estimation of ofloxacin in biological fluids [PDF]
Objective: To evolve simple methods for the assay of ofloxacin in biological fluids. Methods: Simple methods for the estimation of ofloxacin in plasma, saliva and urine employing microbiological assay using plate diffusion technique and by fluorimetric
Chandrasekaran, V +5 more
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Laboratory Survey of Fluoroquinolone Activity [PDF]
Fluoroquinolones are active against a wide variety of bacteria. The antibacterial spectra of fluoroquinolones encompass staphylococci, Bacillus species, and Corynebacterium species implicated in infections of the immunocompromised host ...
Bellido, Francis, Pechère, Jean-Claude
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Design of targeted dosage form of ofloxacin [PDF]
The targeted pro-drug is a classical pro-drug design often representing a non-specific chemical approach to mask undesirable drug properties, such as limited bioavailability, lack of site specificity, and chemical instability. On the other hand, targeted
E. MANOGRAN +3 more
doaj
Study of the formation of artifacts following Dichloromethane reaction with some nitrogenous drugs [PDF]
In this work, the quaternization reaction of some nitrogenous drugs in dichloromethane under stress condition and room temperature at different times are studied.
Amini, M +4 more
core +1 more source
Duration of antibacterial treatment for uncomplicated urinary tract infection in women [PDF]
BAERHEIM, A +5 more
core +1 more source
gyrA mutations and phenotypic susceptibility levels to ofloxacin and moxifloxacin in clinical isolates of Mycobacterium tuberculosis [PDF]
Objectives To compare mutations in the quinolone resistance-determining region of the gyrA gene and flanking sequences with the MICs of ofloxacin and moxifloxacin for Mycobacterium tuberculosis.
Böttger, Erik C. +5 more
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The Pharmacokinetics of ofloxacin, rifampicin, isoniazid and pyrazinmide when administered alone and in combination [PDF]
The present study assesses the bioavailability of Ofloxacin (O) following single oral administration of the drug along with Rifampicin (R), or Isoniazid (H), or Pyrazinamide (Z) or a combination of three drugs. Information on the pharmacokinetics of O
Gurumurthy, Prema +5 more
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