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International Journal of Antimicrobial Agents, 1991
The fluoroquinolone antibiotic agents have been a major advance in the treatment of bacterial infections. The original quinolone nalidixic acid suffered from a narrow spectrum of activity and rapid development of drug resistance. The newer fluoroquinolones have more desirable properties including good oral absorption, enhanced antimicrobial activity ...
Y, Mouton, O, Leroy
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The fluoroquinolone antibiotic agents have been a major advance in the treatment of bacterial infections. The original quinolone nalidixic acid suffered from a narrow spectrum of activity and rapid development of drug resistance. The newer fluoroquinolones have more desirable properties including good oral absorption, enhanced antimicrobial activity ...
Y, Mouton, O, Leroy
+8 more sources
Reactions Weekly, 2010
Ofloxacin is a fluoroquinolone antibiotic first synthesized at Daiichi Pharmaceutical Company, Japan, in 1980. It has the chemical formula 9-fluoro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-(1,2,3-de)1,4- benzoxazine-6-carboxylic acid (Sato et al., 1982; Kumazawa and Yagisawa, 2002).
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Ofloxacin is a fluoroquinolone antibiotic first synthesized at Daiichi Pharmaceutical Company, Japan, in 1980. It has the chemical formula 9-fluoro-3-methyl-10-(4-methyl-1- piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido-(1,2,3-de)1,4- benzoxazine-6-carboxylic acid (Sato et al., 1982; Kumazawa and Yagisawa, 2002).
+5 more sources