Results 71 to 80 of about 27,387 (217)

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat   +7 more
wiley   +1 more source

Analysis of Relationship between Levofloxacin and Corrected QT Prolongation Using a Clinical Data Warehouse [PDF]

open access: yesHealthcare Informatics Research, 2011
ObjectiveThe aim of this study was to examine whether or not levofloxacin has any relationship with QT prolongation in a real clinical setting by analyzing a clinical data warehouse of data collected from different hospital information systems ...
Man Young Park   +7 more
doaj   +1 more source

Systematic review of adverse drug reactions of ofloxacin [PDF]

open access: yes, 2018
Adverse drug reactions (ADRs) are a major cause of morbidity and mortality in countries having limited healthcare resources. Of all the Adverse Drug Reactions, antimicrobials contribute 28% which is highest compared to the other drugs.
Bohra, Pankaj N.   +3 more
core   +1 more source

Juvenile Gangrenous Vasculitis of the Scrotum or Scrotum Lipschütz Ulcers

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Lipschütz genital ulcers are traditionally described in adolescent females and often linked to acute viral infections. Their male counterpart remains poorly characterised. We report a 59‐year‐old man with sudden onset of unilateral necrotic ulcers on the scrotum and inguinal region following a brief febrile episode and mild pharyngitis ...
Francesco Bellinato   +2 more
wiley   +1 more source

Design of targeted dosage form of ofloxacin [PDF]

open access: yesJournal of the Serbian Chemical Society, 2006
The targeted pro-drug is a classical pro-drug design often representing a non-specific chemical approach to mask undesirable drug properties, such as limited bioavailability, lack of site specificity, and chemical instability. On the other hand, targeted
E. MANOGRAN   +3 more
doaj  

Metabolic response of Escherichia coli to subinhibitory concentration of ofloxacin

open access: yes, 2020
Antibiotic resistance is one of the most important problems worldwide. In order to overcome antibiotic resistance, pathogen-antibiotic interactions should be investigated at molecular level.
KOÇAK, ENGİN, ÖZKUL KOÇAK, CEREN
core   +1 more source

LPCAT3 as a Potential Drug Target for Ultraviolet Radiation–Induced Cataract: Insights From Multiomics Analysis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ultraviolet B (UVB) radiation is a major risk factor for cataract development, but the molecular mechanisms underlying this process, particularly the involvement of regulated cell death pathways such as ferroptosis, remain unclear. Transcriptomic, proteomic, and metabolomic analyses were performed on lens tissues from UVB‐induced cataract rat ...
Fei Xu   +4 more
wiley   +1 more source

Effect of ocular compression on intraocular penetration of systemic ofloxacin

open access: yes, 2007
Intraocular levels of ofloxacin are documented after topical and systemic administration, but systemic administration of ofloxacin in ocular compression has not yet been studied.
Can, Murat   +11 more
core   +1 more source

Effect of the microbiome on pathogen susceptibility across four Drosophilidae species

open access: yesInsect Science, EarlyView.
Four Drosophilidae species were used to investigate how variation in the host microbiome influences susceptibility to infection. Microbial composition and abundance differed among species and treatments. The effects of microbiome manipulation on host survival were both species‐ and pathogen‐specific.
Hongbo Sun, Ben Longdon, Ben Raymond
wiley   +1 more source

Topical azithromycin or ofloxacin for endophthalmitis

open access: yes, 2012
Michael W Stewart, Michael L StewartDepartment of Ophthalmology, Mayo Clinic, Jacksonville, FL, USAThe recently published study by Romero-Aroca et al1 raises interesting questions regarding the effect of choice of topical antibiotic (azithromycin versus ...
Stewart MW, Stewart ML
core  

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