Results 11 to 20 of about 27,515 (197)
Sex-dependent role of 20-HETE synthesis in outcome from ischemic stroke in rats. [PDF]
Physiol RepAbstract The lipid mediator 20‐HETE is produced by ω‐hydroxylation of arachidonic acid mediated by cytochrome P450 (CYP) enzymes including CYP4A, which has four distinct isoforms in rodents. Several laboratories demonstrated that 20‐HETE synthesis inhibition reduces infarct volume following middle cerebral artery occlusion (MCAO) in male animals. Here,
Zhang R +4 more
europepmc +2 more sources
Modular detergents tailor the purification and structural analysis of membrane proteins including G-protein coupled receptors [PDF]
, 2020 Detergents enable the purification of membrane proteins and are indispensable reagents instructural biology. Even though a large variety of detergents have been developed in the lastcentury, the challenge remains to identify guidelines that allowfine ...
Almeida, F. +12 more
core +2 more sources
SAGE Open, 2023 Information disclosure, participatory governance, and collaborative innovation are open government data’s (OGD) main goals. Understanding the preconditions that enable the efficient and effective implementation of OGD initiatives is essential for ...
Jinhua Chu, You-Yu Dai, Anyuan Zhong
doaj +1 more source
Factors Influencing Citizens’ Intention to Use Open Government Data—A Case Study of Pakistan
Big Data and Cognitive Computing, 2022 Open government data (OGD) has gained much attention worldwide; however, there is still an increasing demand for exploring research from the perspective of its adoption and diffusion.
Muhammad Mahboob Khurshid +5 more
doaj +1 more source
陆军军医大学学报, 2022 Objective To investigate the effects of oxygen and glucose deprivation/recovery (OGD/R) on apoptosis and pyroptosis of A549 cells, and to explore the possibility of the mutual regulation in apoptosis and pyroptosis.
AN Yuxuan +5 more
doaj +1 more source
Resveratrol promotes the polarization of rat microglial cell line to M2 type with oxygen glucose deprivation/reoxygenation via up-regulating the expression of annexin A1 [PDF]
Jichu yixue yu linchuang, 2021 Objective To explore the role of annexin A1 (ANXA1) in resveratrol regulation of M2 type polarization of rat microglial cell line with oxygen glucose deprivation/reoxygenation (OGD/R) model.
LIN Min, ZHANG Hong-mei
doaj
Biomolecules, 2021 Kaempferol has been shown to protect cells against cerebral ischemia/reperfusion injury through inhibition of apoptosis. In the present study, we sought to investigate whether ferroptosis is involved in the oxygen-glucose deprivation/reperfusion (OGD/R ...
Yuan Yuan +4 more
doaj +1 more source
口腔疾病防治, 2022 Objective Oxygen-glucose deprivation (OGD) is used to mimic ischemia in vitro to observe whether endoplasmic reticulum (ER) stress is involved in human dental pulp cells (hDPCs) after OGD and to better understand the regulatory mechanism of hDPCs in ...
LI Lifen, ZHU Yaqin, JIANG Long
doaj +1 more source
Post-TTM Rebound Pyrexia after Ischemia-Reperfusion Injury Results in Sterile Inflammation and Apoptosis in Cardiomyocytes [PDF]
, 2019 Introduction. Fever is frequently observed after acute ischemic events and is associated with poor outcome and higher mortality. Targeted temperature management (TTM) is recommended for neuroprotection in comatose cardiac arrest survivors, but pyrexia ...
Berger, Felix +6 more
core +1 more source
Protective actions of des-acylated ghrelin on brain injury and blood-brain barrier disruption after stroke in mice [PDF]
, 2016 The major ghrelin forms, acylated ghrelin and des-acylated ghrelin, are novel gastrointestinal hormones. Moreover, emerging evidence indicates that these peptides may have other functions including neuro- and vaso-protection.
Andrews, Zane B. +8 more
core +1 more source