Results 61 to 70 of about 28,063 (214)

Open government data portals in the European Union: A dataset from 2015 to 2017

Data in Brief, 2020
Open government data (OGD) portals are official websites where governments can publish OGD in a controlled way. OGD portals foster discoverability, accountability, and reusability for stakeholders.
Susana de Juana-Espinosa, Sergio Luján-Mora   +1 more
doaj   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Contribution of caspase-mediated apoptosis to the cell death caused by oxygen–glucose deprivation in cortical cell cultures

Neurobiology of Disease, 2005
Several evidences suggest that cell death after cerebral ischemia involves both necrosis and apoptosis. However, it is still unknown which is the relative contribution of both types of cell death.
Cristina Malagelada, Xavier Xifró, Alfredo Miñano, Josefa Sabriá, José Rodríguez-Alvarez   +4 more
doaj   +1 more source

Atomically precise metal cluster enzymes for pathological tissue regeneration

BMEMat, EarlyView.
Schematic illustration of atomically precise metal cluster enzymes (MCEs) for pathological tissue regeneration. Atomically precise MCEs can modulate biological processes, such as attenuation of inflammatory responses, eradication of bacterial pathogens, regulation of angiogenesis, and promotion of cell development.
Ziqiang Xiong, Zhifeng Shi, Mengqing Li, Jien Han, Haoyan Chen, Maofei Ran, Shaojian Zhong, Limin Ma, Chengyun Ning, Youzhun Fan, Zhenghua Tang, Peng Yu   +11 more
wiley   +1 more source

The Study of the Protection Mechanism of Calycosin-7-O-β-d-Glucoside Against Oxygen–Glucose Deprivation/Reperfusion in HT22 Cells Based on Non-Targeted Metabolomics and Network Analysis

Molecules
The cell non-targeted metabolomics technique was used to investigate the potential mechanism of Caly-cosin-7-O-β-d-glucoside (CAG) against cell oxygen–glucose deprivation/reperfusion (OGD/R). The OGD/R-injured HT22 cell model was constructed.
Die Pei, Jieyi Huang, Shanru Chen, Qihui Deng, Cong Nie, Lixia Zhu, Yingfeng Zhang   +6 more
doaj   +1 more source

Role of NKCC1 and KCC2 during hypoxia-induced neuronal swelling in the neonatal neocortex

Neurobiology of Disease, 2023
Neonatal hypoxia causes cytotoxic neuronal swelling by the entry of ions and water. Multiple water pathways have been implicated in neurons because these cells lack water channels, and their membrane has a low water permeability.
Yusuke Takezawa, Rachel Langton, Samuel M. Baule, Miriam Bridget Zimmerman, Stephen Baek, Joseph Glykys   +5 more
doaj   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Unlocking the Future of Insurance: The Power of Open Data, Digital Transformation, and Human Talent

Human Resource Development Quarterly, EarlyView.
ABSTRACT Despite rapid technological advancement in insurance, there remains a critical gap in understanding how open data initiatives affect employee digital competencies and organizational transformation. This research investigates this relationship through a systematic review of 51 scholarly articles published between 2018 and 2024, using structured
Narongsak Sukma, Siriporn Yamnill
wiley   +1 more source

An Investigation on Users’ Perceptions of Open Government Data in Qatar

Human Behavior and Emerging Technologies
This study is aimed at evaluating users’ perceptions of open government data (OGD) in Qatar, addressing disparities between the perceived performance and perceived importance of OGD, and identifying the antecedents and consequences of OGD gaps.
Rima Charbaji El-Kassem, Ali Al-Kubaisi
doaj   +1 more source

Neurotrophin and Trk expression by cells of the human lamina cribrosa following oxygen-glucose deprivation

BMC Neuroscience, 2004
Background Ischemia within the optic nerve head (ONH) may contribute to retinal ganglion cell (RGC) loss in primary open angle glaucoma (POAG). Ischemia has been reported to increase neurotrophin and high affinity Trk receptor expression by CNS neurons ...
Clark Abbot F, Lambert Wendi S, Wordinger Robert J   +2 more
doaj   +1 more source