Results 81 to 90 of about 28,063 (214)
Increased expression of G protein-coupled receptor 84 after cerebral ischemia-reperfusion in rats [PDF]
Jichu yixue yu linchuang, 2021 Objective To determine the expression and function of G protein-coupled receptor 84 (GPR84) in rat cerebral ischemia-reperfusion(I/R). Methods The rat middle cerebral artery occlusion (MCAO) models were performed, and rats were then divided into sham ...
ZHAO Chong-chong, GUO Wen-ting, CAI Hong-bin, WANG Huan
doaj
AntagomiR-451 inhibits oxygen glucose deprivation (OGD)-induced HUVEC necrosis via activating AMPK signaling. [PDF]
PLoS ONE, 2017 Oxygen glucose deprivation (OGD) application in cultured human umbilical vein endothelial cells (HUVECs) mimics ischemic injuries. AntagomiR-451, the miroRNA-451 ("miR-451") inhibitor, could activate pro-survival AMP-activated protein kinase (AMPK ...
Xi Yang +3 more
doaj +1 more source
European Journal of Haematology, Volume 116, Issue 6, Page 724-732, June 2026.ABSTRACT Minimal residual disease (MRD) is a central biomarker in multiple myeloma (MM), offering unprecedented sensitivity for evaluating treatment efficacy and serving as a potential surrogate endpoint. We conducted a comprehensive analysis of clinical trials registered on ClinicalTrials.gov between 2014 and 2025.
Mimi Choon‐Quinones +12 more
wiley +1 more source
Effects and mechanism of dexmedetomidine on neuronal cell injury induced by hypoxia-ischemia
BMC Anesthesiology, 2017 Background The present study aims to investigate the protective effects of dexmedetomidine (DMED) on hypoxia ischemia injury induced by oxygen and glucose deprivation (OGD) in PC12 and primary neuronal cells. Methods PC12 cells exposed to OGD was used to
Ya-Jun Liu +3 more
doaj +1 more source
Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies
ChemBioChem, Volume 27, Issue 9, 14 May 2026.This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci +5 more
wiley +1 more source
Cellular Physiology and Biochemistry, 2015 Background: There is an increasing interest in the role of astrocytes contributing to the intrinsic bioremediation of ischemic brain injury. The purpose of this study was to disclose the effects and mechanism of midazolam (MDZ) on the proliferation and ...
Li Liu +7 more
doaj +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.The functionalized starch modifies the mitochondrial surface and encapsulates resveratrol into the cavity of helices, facilitating a novel mitochondrial transplantation platform (MLSR). Upon internalization in recipient cells, MLSR triggers mitophagy and maintains positive autophagic flux through RIP1/RIP3 pathway inhibition.
Nisha Wang +12 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2015 目的探讨磷酸化Smad3蛋白在神经元样PC12细胞氧糖剥夺中的表达变化。方法利用鼠神经生长因子（NGF）诱导大鼠嗜铬细胞瘤细胞（PC12）向神经元样细胞转化,应用无糖DMEM培养液联合连二亚硫酸钠（Na2S2O4）构建氧糖剥夺模型（oxygen-glucose deprivation,OGD）,体外模拟神经元缺血性损伤。MTT检测神经元样细胞OGD 0,3,6和12h存活率,Western blot检测OGD前后磷酸化Smad3蛋白表达。结果成功建立神经元样PC12细胞的OGD模型;OGD ...
徐仲航 +7 more
doaj
InformaticsAn Open Government Data (OGD) portal assessment is necessary to track and monitor the progress of the OGD initiative and to drive improvement. Although OGD benchmarks typically focus on assessing and ranking OGD portals, few have been developed ...
Sahaporn Sripramong +4 more
doaj +1 more source
PLoS ONE, 2014 Purinergic P2X and P2Y receptors are broadly expressed on both neurons and glial cells in the central nervous system (CNS), including dentate gyrus (DG).
Giovanna Maraula +9 more
doaj +1 more source