Results 71 to 80 of about 28,063 (214)

The Endothelial CXCR Family in Vascular Health and Disease

open access: yesiNew Medicine, EarlyView.
ABSTRACT Endothelial cells (ECs) form the dynamic interface between blood and tissue, serving as key regulators of vascular homeostasis, inflammation, and repair. Among the molecular systems governing endothelial behavior, the C‐X‐C motif chemokine receptor (CXCR) family—originally characterized in immunology for its roles in leukocyte trafficking and ...
Zhiming Wu   +4 more
wiley   +1 more source

Charting the Evolution of Open Data Business Models: Insights From a Systematic Review and Thematic Analysis of a Decade

open access: yesStrategic Change, EarlyView.
ABSTRACT This article presents a decade of research on Open Data Business Models (ODBM), aiming to identify conceptual gaps, categorize thematic trends, and propose an integrative framework. This paper, based on a systematic literature review (SLR) of 60 peer‐reviewed studies, develops a coherent framework that explains how ODBMs are formed, adapted ...
Saeed Rouhani   +3 more
wiley   +1 more source

Factors influencing open government data post-adoption in the public sector: The perspective of data providers.

open access: yesPLoS ONE, 2022
Providing access to non-confidential government data to the public is one of the initiatives adopted by many governments today to embrace government transparency practices.
Mimi Nurakmal Mustapa   +2 more
doaj   +1 more source

OGD Heartbeat: Cities’ Commitment to Open Data

open access: yesJeDEM - eJournal of eDemocracy and Open Government, 2015
This paper develops and tests a theoretical model, which proposes to examine cities’ commitment to the concept of open government data (OGD) according to three typical levels. Level 1, Way of Life, indicates high commitment to OGD; Level 2, On the Fence, represents either a low or erratic commitment; Level 3, Lip Service, refers to either scarce or no ...
Karin Nahon   +2 more
openaire   +2 more sources

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

open access: yesAndrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz   +12 more
wiley   +1 more source

Grifolin attenuates white matter lesion in oxygen/glucose deprivation

open access: yesTranslational Neuroscience, 2017
The present study evaluates the effect of grifolin (GFL) in oxygen/glucose deprivation (OGD) induced white matter lesion. Injury induced with OGD was found to be significant at the 9th h of OGD induction and the effect of GFL on the proliferation of ...
Yanqin Ying, Jing Tang, Wei Chen, Nan Li
doaj   +1 more source

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

Apigenin attenuates myocardial ischemia-reperfusion injury through miR-448/SIRT1 axis [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): Myocardial ischemia/reperfusion injury (MIRI) is the primary pathological injury following ischemic cardiomyocyte therapy, but there are few effective treatments available for MIRI. Apigenin (API) is an active ingredient of herbal medicine.
Chenchen Tian   +5 more
doaj   +1 more source

Cardiac shock wave therapy-induced exosome derived from OGD/R-treated H9c2 cells carrying miR-98-5p promote HUVECs angiogenesis

open access: yesScientific Reports
Cardiac shock wave therapy (CSWT) as an effectual therapy can activate the function of exosomes to a certain extent. Here, we attempted to examine the role of CSWT in exosome released from ischemic cardiomyocytes and its function in myocardial ischemia ...
Lizhou Wu   +5 more
doaj   +1 more source

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