Results 191 to 200 of about 22,588 (217)

OGT's inner circle: Protein interactions and functional impact

Advances in Biological Regulation
The modification of nuclear, cytoplasmic, and mitochondrial proteins by O-linked β-N-acetylglucosamine (O-GlcNAc) has emerged as an essential post-translational modification in mammals. More than 5000 human proteins are subject to O-GlcNAcylation, influencing key cellular processes such as signal transduction, epigenetic regulation, transcription ...
Fiddia Zahra, Natasha E. Zachara
openaire   +2 more sources

The E. coli ogt gene

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1990
G P, Margison, D P, Cooper, P M, Potter
openaire   +2 more sources

ULK1-dependent phosphorylation of OGT instructs the tumorigenicity of O-GlcNAcylation

Science China Life Sciences
Investigations from the last four decades have correlated high O-linked N-acetylglucosamine (O-GlcNAc) levels with various cancer types, but it is not known how OGT responds to diverse nutrients to finetune cellular O-GlcNAcylation levels. Herein we identified a critical OGT phosphorylation site by unc-51 like autophagy activating kinase 1 (ULK1) under
Zhuan, Lv, Qingen, Da, Yumiao, Li, Aiyun, Yuan, Guangcan, Shao, Xiaoxuan, Lu, Yue, Wang, Xuefang, Zhang, Jingjing, Liu, Meng-Qiu, Dong, Yuanyuan, Ruan, Chen, Wu, Kunfu, Ouyang, Jing, Li   +13 more
openaire   +2 more sources

OGT: optimize graph then training GNNs for node classification

Neural Computing and Applications, 2022
Quanmin Wei, Jinyan Wang, Jun Hu, Xianxian Li, Tong Yi   +4 more
openaire   +1 more source

OGT-regulated O-GlcNAcylation promotes the malignancy of colorectal cancer by activating STAT2 to induce macrophage M2: OGT protein macromolecule action

International Journal of Biological Macromolecules
O-GlcNAcylation, as an important glycosylation modification, plays a key role in cancer progression. The purpose of this study was to investigate the role of OGT (O-GlcNAc transferase) in the regulation of O-GlcNAcylation and macrophage M2 polarization, especially in the malignant progression of cancer.
Meng, Wang, Li, Qiao, Li, Jin, Yuanyuan, Chen, Xing, Wen, Haijuan, Wang   +5 more
openaire   +2 more sources

A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation

Cell Metabolism, 2021
Pedro Latorre, Christopher F Bennett, Elizabeth A Perry   +2 more
exaly  

OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy

Cell Reports, 2021
Koichi Murakami, Daisuke Kurotaki, Yumi Fukuchi   +2 more
exaly  

OGT controls mammalian cell viability by regulating the proteasome/mTOR/ mitochondrial axis

Proceedings of the National Academy of Sciences of the United States of America, 2023
Xiang Li, Xiaojing Yue, David A Scott
exaly  

OGT-rearranged Acral Mesenchymal Neoplasms

American Journal of Surgical Pathology, 2021
Jen-Chieh, Lee, Tsung-Han, Hsieh, Yu-Chien, Kao   +2 more
openaire   +2 more sources

Treatment of Gaucher's disease with OGT 918

The Lancet, 2000
  +4 more sources