Results 61 to 70 of about 7,428,510 (315)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Evaluation of the performance of rear dump trucks for oil shale mining and hauling

open access: yes, 2022
Technical memorandum no. 67-42.Includes drawings.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated ...

core  

Genetic analysis of protein content and oil content in soybean by genome-wide association study

open access: yesFrontiers in Plant Science, 2023
Soybean seed protein content (PC) and oil content (OC) have important economic value. Detecting the loci/gene related to PC and OC is important for the marker-assisted selection (MAS) breeding of soybean.
Hui Jin   +8 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the fourth meeting

open access: yes, 2022
Includes charts.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical Advisory Committee was formed by Socony Mobil, ESSO Research and ...

core  

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

Shale oil technical advisory committee, minutes of the seventeenth meeting

open access: yes, 2022
Includes charts.Three unscanned drawings, contact the Library for more information.These minutes were recorded at the Technical Advisory Committee meetings and include agenda, budget, and technical reports about work performed at Anvil Points.A Technical

core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

open access: yesMolecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim   +11 more
wiley   +1 more source

Retorting costs for a 50,000 B/CD oil shale processing complex

open access: yes, 2022
Technical memorandum no. 67-39.These technical memoranda pertain to work performed at Anvil Points.The United States Bureau of Mines facility at Anvil Points, near Rifle, Colorado, was reactivated starting in May 1964 and was operated during 1965, 1966 ...

core  

Combining ability and heritability estimates of main agronomic characters in rapeseed breeding lines using line × tester analysis [PDF]

open access: yesJournal of Agricultural Sciences (Belgrade), 2012
To estimate the general and specific combining ability (GCA and SCA) effects of plant height, yield components, seed yield and oil content, three testers and six lines of spring type of rapeseed varieties were crossed using line × tester fashion ...
Rameeh Valiollah
doaj   +1 more source

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