Results 41 to 50 of about 69,580 (257)
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source
, 2022 FTIR-spectra of pure curcumin, PEG-Curcumin, PEG, PEG-CUR Ointment and PEG-CUR Ointment with cremophore.
Khalid Mahmood (259708) +6 more
core +1 more source
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
Фармацевтичний журнал, 2018 An analysis of the state of modern resources for pharmacotherapy of foot mycosis was carried out. It showed that the creation of semisolid dosage forms for the topical skin, foot web space and nail treatment with bioactive compound from the group of ...
V. V. Luc +3 more
doaj +1 more source
Standardization of “ANTIBOVASIN” ointment [PDF]
, 2018 The method of standardizing the Antibovasin ointment has been developed. Such indicators as appear-ance, authenticity, pH, nominal filling capacity of the tube, particle size, microbiological purity, homoge-neity and quantitation of active substances of
Aminov, S.N +2 more
core
This study introduces an innovative eco-friendly gel ointment designed to treat burns and minor wounds, incorporating cleaned paper waste into its formulation.
Yuri Gonzales
core +7 more sources
Comparative Study of Efficacy of Dhattura Beeja Ointment & Sarshapa Ointment in the Management of Vipadika (Cracked heel) [PDF]
, 2020 Background: Vipadika is one of the Vataja Nanatmaja Vikara which is also considered as Kshudra Kustha. The patient suffering with disease feel severe pain and it increases with the progression of disease. Ayurveda described various therapeutic approaches
Meena, Raju +2 more
core +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang +7 more
wiley +1 more source
Development of a Method of Analysis of Ofloxacin in the Complex Preparation "Ofloxazol"
Разработка и регистрация лекарственных средств, 2021 Introduction. The creation of new effective antibacterial drugs for the treatment and prevention of purulent-inflammatory diseases is an urgent task of modern pharmacy. Active use in the treatment of purulent infection is found by chemotherapeutic agents
T. A. Kobeleva +3 more
doaj +1 more source