Results 51 to 60 of about 57,101 (269)

Flexible Implantable Silicon Carbide Multi‐Electrode Array (MEA) for Cell Multichannel Recording and Cell Ablation

open access: yesAdvanced Materials Technologies, EarlyView.
Flexible silicon carbide (SiC) microelectrode arrays enable high‐fidelity, multichannel cell extracellular recording and precise localized ablation. SiC has been extensively evaluated to persist long‐term in chronic physiological conditions while remaining robust, with excellent electrical and electrochemical stability.
Minh Anh Huynh   +4 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

open access: yesAdvanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen   +14 more
wiley   +1 more source

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

open access: yesAdvanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang   +9 more
wiley   +1 more source

STIMULATION OF CICATRIX AND EPITHELIUM MAKING PROCESES, BY USE OF SOME AROMATIC PLANT EXTRACTS

open access: yesScientific Papers Animal Science and Biotechnologies, 2023
This experiment has as purpose an evaluation of cicatrix stimulation and healing capacity of some accidental wounds produced by different body regions to a livestock of 20 horses, young stock and adult animals, during the year 2007, by local treatment ...
O. NEGREA   +3 more
doaj  

Reinnervation of Muscle Targets Enhances the Separability of Motor Unit Signals Following Peripheral Nerve Transfers

open access: yesAdvanced Science, EarlyView.
Injured or cut peripheral nerves can be surgically rerouted to reinnervate new muscle targets. This study demonstrates reinnervated muscles exhibit enhanced separability between individual motor unit signals, which can simplify signal recording and decomposition. These findings highlight the potential of reinnervated muscle to serve as a key biological
Kiara N Quinn   +11 more
wiley   +1 more source

Inhibitory Effects of a Herbal Ointment against Pseudomonas aeruginosa

open access: yesMedical Laboratory Journal, 2019
Background and Objectives: Pseudomonas aeruginosa is a gram negative opportunistic pathogen and an important cause of wound infections and nosocomial infections.
Maryam Meskini   +2 more
doaj  

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

open access: yesAdvanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang   +4 more
wiley   +1 more source

Formulation and evaluation of antibacterial activity of nanoparticles ointment preparation using Blimbi extract

open access: yesPharmaceutical and Biomedical Research, 2018
Indonesia has various beneficial plant species which have not been cultivated well yet. Blimbi (Averrhoa bilimbi L.) is among those plants which have antibacterial activities against Staphylococcus aureus and Escherichia coli.
Nia Lisnawati   +2 more
doaj  

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