Results 71 to 80 of about 69,580 (257)

Experience in using povidone-iodine to treat superficial and full-thickness burns

Амбулаторная хирургия, 2019
Thermal injuries are now ranked number one among injuries, and incidence of injury-related complications, especially infectious and purulent, does not decrease in surgical practice, despite the modern methods for treatment and prevention.
O. V. Vladimirova, P. M. Lavreshin, V. I. Vladimirov, A. E. Rybalko, I. A. Zybinskiy   +4 more
doaj   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Tacrolimus ointment in the management of atopic dermatitis

, 2009
Antonello Baldo, Mariana Cafiero, Paola Di Caterino, Luisa Di CostanzoDepartment of Dermatology, University of Naples Federico II, Naples, ItalyAbstract: Atopic dermatitis (AD) is a chronic, relapsing, highly pruritic inflammatory skin disease.
Paola Di Caterino, Mariana Cafiero, Luisa Di Costanzo, Antonello Baldo   +3 more
core  

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

In Vitro Antimicrobial, Antioxidant and In Vivo Wound Healing Activity on Wistar Albino Rats by Plant-Mediated Synthesis of CuO Nanoparticles from the Fruit Extract of Diplocyclos palmatus (L) C. Jeffrey [PDF]

Nanomedicine Journal
This study investigates the in vitro antimicrobial, antioxidant, and in vivo wound healing activities of copper oxide (CuO) nanoparticles synthesized from the Diplocyclos palmatus (L) C. Jeffrey fruit extract.
Parethe Gurusamy Thangam, Rajesh Pattulingam, Kavica Sathasivam, Balaji Murugesan, Velmani Vellaiyan   +4 more
doaj   +1 more source

Critical evaluation of cadexomeriodine ointment and povidone-iodine sugar ointment

, 2009
a b s t r a c t Topical iodine forms are used for infected and necrotic pressure ulcers. Despite antimicrobial advantages several potential disadvantages were observed with controversial results.
Satoshi Fujii, Yasuhiro Noda, Kiori Fujii   +2 more
core  

Comparative effect of tacrolimus 0.1% ointment and clobetasol 0.05% ointment in patients with oral lichen planus. [PDF]

, 2008
BACKGROUND: Oral lichen planus (OLP) is considered to be an autoimmune disease of unknown aetiology that affects the mucosae, especially the oral cavity.
G. Di Lorenzo, MARTINELLI, Nicola, Gelio S., Pasquale Mansueto, Pier Francesco Nocini, MANSUETO, Pasquale, FIOR, Andrea, CORROCHER G, DI LORENZO, Gabriele, CORROCHER, Giovanni, Stefano Gelio, CORROCHER, Roberto, FIOR A, Gabriele Di Lorenzo, Roberto Corrocher, Di Lorenzo G., NOCINI PF, BAMBARA, Lisa Maria, Maria Luisa Pacor, Giovanni Corrocher, P. Mansueto, MARTINELLI N, LOMBARDO G, PACOR ML, Nicola Martinelli, GELIO S, Lisa Maria Bambara, Andrea Fior, Mansueto P., CORROCHER R, Giorgio Lombardo, BIASI D, BAMBARA LM, LOMBARDO, Giorgio, PACOR, Maria Luisa, BIASI, Domenico, Domenico Biasi, S. Gelio, NOCINI, Pier Francesco   +38 more
core   +1 more source

ICOS‐ImmunoPET Monitors T Cell Activation After Combination Immune Checkpoint Blockade in a Mouse Model of Melanoma Brain Metastasis

Advanced Science, EarlyView.
ICOS‐immunoPET noninvasively visualizes activated T cells in melanoma brain metastases following combined anti‐PD‐1/anti‐CTLA‐4 therapy. Clinical translation of this imaging approach may improve patient stratification and treatment monitoring and serve as a quantitative imaging endpoint to support immunotherapy development and clinical trials in brain ...
Renesmee C. Kuo, Rohit Verma, Sydney C. Nagy, Mausam Kalita, Samuel Aubert, Josué Ballesteros‐Álvarez, Pedro Machado Almeida, Hannes Vogel, Israt S. Alam, Michael Lim, Michelle L. James   +10 more
wiley   +1 more source

Rhoifolin Alleviates Ulcerative Colitis by Targeting NMNAT1 and Activating SIRT1‐FOXO1 Signaling to Enhance ILC3s Effector Function

Advanced Science, EarlyView.
Rhoifolin directly targets NMNAT1, thereby activating nicotinamide salvage pathway and promoting intracellular NAD+ biosynthesis. Elevated NAD+ levels enhance SIRT1 activity, leading to FOXO1 deacetylation and nuclear translocation. Nuclear FOXO1 subsequently binds to the IL‐22 promoter, upregulating IL‐22 transcription and potentiating ILC3 effector ...
Hongqiong Yang, Yishu Zhang, Sijia Feng, Xiaoqing Ma, Jiayi Feng, Junwei Wang, Jialin Gao, An Pan, Dapeng Wu, Kang Ding, Caijuan Zheng, Qi Lv, Lihong Hu   +12 more
wiley   +1 more source

Study of the antimicrobial activity of phytoointment for treatment of mechanical damages of dairy tissue

Annals of Mechnikov's Institute, 2019
Introduction. One of the common pathologies found in gynaecological practice is cracking nipples, which represent the rupture of an external sensitive epidermis due to its mechanical damage. Cracks have different shapes (straight and stellar), as well as
S Zuikina, L Vyshnevska, L Silaeva
doaj