Results 101 to 110 of about 21,271 (292)
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis triggers hippocampal SIRT7 loss, promoting histone H2B succinylation and activation of the PD‐1/PD‐L1–PINK1 axis. This metabolic‐epigenetic cascade drives aberrant mitophagy and neuronal injury, ultimately causing cognitive deficits. Targeting SIRT7‐dependent succinylation offers a potential strategy to protect brain function during sepsis ...
Na Meng +12 more
wiley +1 more source
Electronic Physician, 2017 Background: Nipple fissure is a common problem in breastfeeding women, and the main reason for the early discontinuation of breastfeeding. Objective: To determine the effect of Saqez (Pistacia atlantica) ointment on the treatment of nipple fissure and
Nayereh As’adi +3 more
doaj +1 more source
Ointments for the protection against organophosphate poisoning
, 1982 Ointments for the protection against poisoning of the skin by highly toxic organophosphates or organo-phosphate insecticides were prepared and examined for their protective effect both on guinea-pig skin in vitro and on guinea-pigs in vivo.
Ceulen, B.I. +4 more
core
Pharmaceutical bioavailability of combined ointments with izohydrafural and methyluracil [PDF]
, 2012 Introduction: A difficult problem in the human pathology is the purulent infections due to the necessity of taking several drugs for a complex action such as: antimicrobial, regenerating, anti-inflammatory and analgesic.
Vîslouh, Oxana +4 more
core +1 more source
Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair
Advanced Science, EarlyView.Schematic diagram illustrating the Dab1‐linked hypoxia signaling pathway that accelerates angiogenesis and consequent nerve regeneration. Following PNI, a hypoxic microenvironment develops. Hypoxia induces macrophage Dab1 phosphorylation, resulting in NHE‐1 upregulation, HIF‐1α stabilization, and VEGF‐A expression. This cascade promotes angiogenesis in
Xiongyao Zhou +14 more
wiley +1 more source
Kampo traditional ointments for wound healing
, 2023 International audienceThe traditional Japanese herbal medicine, named Kampo, offers treatments for a wide range of therapeutic indications including dermatological ones.
Obeid, Patricia +8 more
core +2 more sources
Nanoparticles assisted intra and transdermic delivery of antifungal ointment: an updated review
Discover NanoThis review paper highlights the trans-dermic delivery of nanoparticles (NPs) based antifungal ointments with the help of nanotechnology. It also describes the novel trans-dermal approach utilizing various nanoparticles which enables an efficient ...
Nazia Tarannum +3 more
doaj +1 more source
Wound healing effects of paste type acellular dermal matrix subcutaneous injection
Archives of Plastic Surgery, 2018 Background Acellular dermal matrix (ADM) helps wound healing by stimulating angiogenesis, acting as a chemoattractant for endothelial cells, providing growth factors, and permitting a substrate for fibroblasts to attach.
Jin Ho Lee +6 more
doaj +1 more source
Advanced Science, EarlyView.Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu +12 more
wiley +1 more source