Results 61 to 70 of about 21,271 (292)

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Clinical Impact of MGMT Promoter Methylation in IDH‐Mutant Gliomas: Influence of Threshold Selection and Clinical Confounding

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background The clinical relevance of MGMT promoter methylation in IDH‐mutant gliomas remains controversial in the era of molecular classification. We aimed to systematically evaluate its clinical relevance by integrating quantitative assessment, cutoff exploration, and adjustment for clinical confounding.
Haihui Jiang, Linxi Cao, Xiaodong Chen, Siqi Tong, Qinghui Zhu, Jun Yang, Song Lin, Yong Cui   +7 more
wiley   +1 more source

Differences in the rheological properties and mixing compatibility with heparinoid cream of brand name and generic steroidal ointments: The effects of their surfactants [PDF]

, 2016
Most steroidal ointments contain propylene glycol (PG) and surfactants, which improve the solubility of corticosteroids in white petrolatum. Surfactants aid the uniform dispersal of PG within white petrolatum.
Yutani, Reiko, Kodani, Rhu-ichi, Kitagawa, Shuji, Teraoka, Reiko   +3 more
core   +1 more source

Perceived Impacts and Predictors of Cannabis Products Used by Patients with Rheumatologic Conditions in Alberta, Canada: A Multivariable Analysis of Cross‐Sectional Survey Data

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize cannabis product choices (cannabinoid content and formulation) among patients with rheumatologic conditions and their associations with patient factors, patient‐reported perceived side effects, and positive impacts.
Susan Zhang, Samuel A.J. Lowe, Frank Sun, Allyson Jones, Tarek Turk, Joanne Olson, Pauline Paul, Shelby Yamamoto, Linda Kolewaski, Elaine Yacyshyn, Cheryl A. Sadowski   +10 more
wiley   +1 more source

Relationship between the usability and physicochemical properties of triamcinolone acetonide ointments [PDF]

, 2013
The purpose of this study was to examine the physicochemical properties of TA ointments and conduct a human sensory test to assess the properties of those ointments.
村田, 勇, 古屋, 香代子, 木村, 昌行, 井上, 裕, 金本, 郁男, 前田, 力丸   +5 more
core   +3 more sources

Study of basis-transmitter influence on biopharmaceutical properties of diltiazem nasal dosage form

Zaporožskij Medicinskij Žurnal, 2013
It is set that the type of basis-transmitter has an influence on release of diltiazem from intranasal ointments. Variance analysis of researches results showed that transmitter on the basis of methylcellulose glycerogel provides optimal diltiazem ...
V. V. Gladyshev, G. K. Kuchina, B. S. Burlaka   +2 more
doaj   +1 more source

Feasibility and Limitations of the Advanced Replica Process for Bioactive Glasses

Advanced Engineering Materials, EarlyView.
Periodic 3D‐printed Kelvin‐cell templates enable a controlled advanced replica process for fabricating highly porous glass lattices. Across P45K9, 45S5, and 13–93, material‐dependent differences in coating, burnout, and shrinkage lead to distinct strut morphologies, while comparable final porosities of 83%–88% are retained.
Swantje Funk, Elisabeth Keck, Alberto López‐Grande, Delia S. Brauer, Tobias Fey   +4 more
wiley   +1 more source

Application of new original ointments for treatment of burns with experimental pseudomonas infection [PDF]

Саратовский научно-медицинский журнал, 2011
The research goal is to assess the efficacy of treatment with two new original ointments for burns with experimental pseudomonas infection. Burns have been caused by laser to three groups of white rats (20 animals in each group).
Shub G. М., Alipov V. V., Lebedev М. S., Dobreikin Е.А., Alipov N. V., Pronina E.A., Raikova S. V., Shapoval O. G.   +7 more
doaj  

Effects of Piper crocatum leaf extract-based ointments on bacteria associated with diabetic ulcers: an in vitro study [PDF]

Pharmaciana
Diabetic patients with poor blood glucose control are highly susceptible to developing secondary infections, which can lead to the development of prolonged diabetic ulcers. Therefore, a suitable medication that may effectively prevent the occurrence of
Yudha Rizky Nuari, Mila Abusri, Wahyu Yuntari, Oca Maharani Tryadi, Fiarriescha Marra Ardhiana   +4 more
doaj   +1 more source

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

Advanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee, Xinyi Wang, Sirui Li, Jihyang Park, Hyunseok Lee, Jianting Yao, Kedar Narayan, Yuqi Wang, Jiashu Ren, Yueqi Deng, Salahuddin Ahmed, Denver I. Greenawalt, Archana Pandiyan, Loganathan Veeramuthu, Chi‐Ching Kuo, Tao Zhou   +15 more
wiley   +1 more source