Results 101 to 110 of about 2,813,688 (177)

Active elimination of the marine biotoxin okadaic acid by P-glycoprotein through an in-vitro gastrointestinal barrier

, 2014
The consumption of okadaic acid (OA) contaminated shellfish can induce acute toxic symptoms in humans such as diarrhea, nausea, vomiting and abdominal pain; carcinogenic and embryotoxic effects have also been described.
Ehlers, A., These,A., Lampen, A., Preiss-Weigert, A., Hessel, S.   +4 more
core   +1 more source

First identification of a C9-diol-ester of okadaic acid in Dinophysis acuta from Galician Rías Baixas (NW Spain)

, 2018
Dinoflagellates of the genus Dinophysis produce okadaic acid (OA) and analogues. Cultures of a strain of Dinophysis acuta isolated from the Galician Rías contained high levels of pectenotoxins but little OA. Isomeric forms of the latter were suspected as
Garcia-portela, Maria, Hess, Philipp, Sibat, Manoella   +2 more
core   +1 more source

The Effect of Okadaic Acid on Cultured Tissues of Bivalves, Mytilus galloprovincialis and Crassostrea gigas

, 1994
Okadaic acid, which is known to be a cause of the diarrhetic shellfish poisoning, was tested for its effect on the morphology of primary cultures established from two bivalve species, Mytilus galloprovincialis and Crassostrea gigas.
Ogata, Hiroshi, 青野, 英明, 2039, Aono, Hideaki, 80443357, 515, 尾形, 博, オガタ, ヒロシ, アオノ, ヒデアキ, 10371874   +9 more
core  

Okadaic acid blocks the effects of 5-aza-2-deoxycytidine on consolidation, acquisition and retrieval of morphine-induced place preference in rats

, 2014
Recent studies indicated that epigenetic modification, especially DNA methylation, play an important role in the persistence of addiction-related memory.
Sui, Nan, Han, Jin, Zhang, Jian-Jun
core   +1 more source

Bioavailability and transplacental passage of the embryotoxic marine biotoxin okadaic acid

, 2010
The marine biotoxine okadaic acid (OA) is produced by dinoflagellates and can accumulate in filter feeding bivalves (mussels, oysters, etc.). While OA does not affect the bivalves, most of them are able to cause harm in humans.
These,A., Preiss-Weigert,A., Lampen,A., Ehlert,A., Kneuer,C., Scholz,J.   +5 more
core  

Studies on the release of okadaic acid in Prorocentrum lima and the methodological optimization of okadaic acid purification

, 2007
本研究探討黑海綿酸的提純最適化，在研究初期發現藻細胞在培養至穩定期後，釋放黑海綿酸到培養液中的濃度大量提高，不利於從藻細胞內提純黑海綿酸，此時針對培養液中黑海綿酸的提純，較從藻細胞後內提純更簡單，因此本研究以合成吸附樹脂SP825吸附培養液中的黑海綿酸後，再行脫附提純。SP825對黑海綿酸吸附實驗中，發現SP825吸附承載量至少為4.736 mg/g，而SP825對黑海綿酸的脫附率可達96.9 %，整個操作不僅能完全吸附培養基中的黑海綿酸，並可利用甲醇來達到脫附毒素的目的，增加量化生產時濃縮操作的方便性，
Wu, Jain-Shin, 吳建欣
core  

A Dinophysistoxin 2-like Okadaic Acid Isomer Present in Bivalves and Water Column: Temporal and Spatial Distribution in the Northwest Iberian Peninsula. [PDF]

Toxins (Basel)
Blanco J, Moroño Á, Arévalo F, Correa J, Rossignoli AE, Lamas JP.   +5 more
europepmc   +1 more source

AMPK-PP1/PP2 axis regulates GSDMD-mediated pyroptosis via phosphorylation. [PDF]

Front Oncol
Zhang T, Gao C, Xu J, Zhang W, Xing Y, Li G, Li M, Guo Y, Zhang Z, Zheng P, Zheng X, Chu X.   +11 more
europepmc   +1 more source

Salbutamol and Formoterol Attenuate Okadaic Acid-Induced Cytotoxicity in Undifferentiated PC-12 Cells: Evidence for a β2-Adrenergic Receptor-Independent Protective Component. [PDF]

Curr Issues Mol Biol
Kotsoni A, Ioannou E, Barmparousi E, Zacharia LC.   +3 more
europepmc   +1 more source

Development of Analytical Methods for Multiple Phycotoxins in Fish Plasma. [PDF]

ACS Omega
Hernandez OS, Sanderson MP, Latour RJ, Smith JL.   +3 more
europepmc   +1 more source