Combined effects of valproate and naringin on kidney antioxidative markers and serum parameters of kidney function in C57BL6 mice [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2023 Valproate is known to disturb the kidney function, and high doses or prolonged intake may cause serum ion imbalance, kidney tubular acidosis, proteinuria, hyperuricosuria, polyuria, polydipsia, and dehydration.
Jutrić David +6 more
doaj +2 more sources
The effects of simvastatin and fenofibrate on malondialdehyde and reduced glutathione concentrations in the plasma, liver, and brain of normolipidaemic and hyperlipidaemic rats [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2023 The objective of study was to investigate the effects of different doses of simvastatin and fenofibrate on malondialdehyde (MDA) and reduced glutathione (GSH) in the plasma, liver, and brain tissue of male normolipidaemic and hyperlipidaemic rats ...
Vukšić Antonija +7 more
doaj +2 more sources
Pro-oxidant potency of clothianidin in rainbow trout [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2021 Clothianidin is a systemic neonicotinoid insecticide interfering with the central nervous system by acting as a nicotinic acetylcholine receptor agonist.
Fakhereddin Tarek, Doğan Demet
doaj +2 more sources
Protective effects of resveratrol against fumonisin B1-induced liver toxicity in mice [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2023 The aim of this study was to investigate the effects of resveratrol against fumonisin B1 (FB1)-induced liver toxicity, as, to the best of our knowledge, these effects have not been investigated yet, even though the toxic effects and mechanisms of FB1 and
Yalçın Rıza +3 more
doaj +2 more sources
Effects of naringin and valproate interaction on liver steatosis and dyslipidaemia parameters in male C57BL6 mice [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2022 Valproate is a common antiepileptic drug whose adverse effects include liver steatosis and dyslipidaemia. The aim of our study was to see how natural flavonoid antioxidant naringin would interact with valproate and attenuate these adverse effects.
Jutrić David +8 more
doaj +2 more sources
Effects of concomitant use of THC and irinotecan on tumour growth and biochemical markers in a syngeneic mouse model of colon cancer [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2023 Clinical treatment with the antineoplastic drug irinotecan (IRI) is often hindered by side effects that significantly reduce the quality of life of treated patients.
Žunec Suzana +8 more
doaj +2 more sources
Redox and biometal status in Wistar rats after subacute exposure to fluoride and selenium counter-effects [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2022 This study aimed to investigate the effect of 150 mg/L sodium fluoride (NaF) on redox status parameters and essential metals [copper (Cu), iron (Fe), and zinc (Zn)] in the blood, liver, kidney, brain, and spleen of Wistar rats and to determine the ...
Radovanović Jelena +12 more
doaj +2 more sources
Cherry laurel fruit extract counters dimethoate-induced reproductive impairment and testicular apoptosis [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2020 Dimethoate is an organophosphorus pesticide used against agricultural insects, which causes oxidative stress and damage in many organs, including the reproductive ones. Cherry laurel (Laurocerasus officinalis Roem.) fruit is rich in vitamins and phenolic
Bakır Elçin +7 more
doaj +2 more sources
Metabolic and genetic derangement: a review of mechanisms involved in arsenic and lead toxicity and genotoxicity [PDF]
Arhiv za Higijenu Rada i Toksikologiju, 2022 Urbanisation and industrialisation are on the rise all over the world. Environmental contaminants such as potentially toxic elements (PTEs) are directly linked with both phenomena.
Sadiku Olubusayo Olujimi +1 more
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Oxidative stress under general intravenous and inhalation anaesthesia. [PDF]
Arh Hig Rada Toksikol, 2020 Oxidative stress occurs when reactive oxygen species (ROS) production overwhelms cell protection by antioxidants. This review is focused on general anaesthesia-induced oxidative stress because it increases the rate of complications and delays recovery ...
Kundović SA +4 more
europepmc +3 more sources