Results 11 to 20 of about 84,234 (301)

Olanzapine-induced neutropenia [PDF]

Mental Illness, 2015
Olanzapine-induced neutropenia is a rare adverse effect that is currently poorly described in literature. Although neutropenia is a known adverse effect of clozapine, it has been associated with the use of other antipsychotic medications like olanzapine. This case report describes and reviews a case of olanza-pine-induced neutropenia in a schizophrenic
Kirti Malhotra, Priscilla Vu, Danielle H. Wang, Hank Lai, Lawrence R. Faziola   +4 more
openaire   +3 more sources

Olanzapine leads to nonalcoholic fatty liver disease through the apolipoprotein A5 pathway

bioRxiv, 2021
The antipsychotic drug olanzapine was reported to induce nonalcoholic fatty liver disease (NAFLD), whereas the underlying mechanism remains incompletely understood.
Rong Li, Wenqiang Zhu, Piaopiao Huang, Yang Yang, F. Luo, W. Dai, Li Shen, Wenjing Pei, Xiansheng Huang   +8 more
semanticscholar   +1 more source

Risk of major adverse cardiovascular events with aripiprazole versus olanzapine, quetiapine, and risperidone in severe mental illness: a target trial emulation [PDF]

Nat Commun
Alvin Richards-Belle, Naomi Launders, Sarah Hardoon, K All- Man, Neil M Davies, Elvira Bramon, Joseph Hayes, D Osborn   +7 more
openalex   +2 more sources

CYP1A2 expression rather than genotype is associated with olanzapine concentration in psychiatric patients

Scientific Reports, 2023
Olanzapine is a commonly prescribed atypical antipsychotic agent for treatment of patients with schizophrenia and bipolar disorders. Previous in vitro studies using human liver microsomes identified CYP1A2 and CYP2D6 enzymes being responsible for CYP ...
Ferenc Fekete, Ádám Menus, Katalin Tóth, Ádám Ferenc Kiss, Annamária Minus, Dávid Sirok, Aleš Belič, Ádám Póti, Gábor Csukly, Katalin Monostory   +9 more
doaj   +1 more source

Olanzapine for the Treatment of Advanced Cancer-Related Chronic Nausea and/or Vomiting: A Randomized Pilot Trial.

JAMA Oncology, 2020
Importance Nausea and vomiting, unrelated to chemotherapy, can be substantial symptoms in patients with advanced cancer. Objective To evaluate the utility of olanzapine for treating chronic nausea/vomiting, unrelated to chemotherapy, in patients with ...
R. Navari, Cameron M. Pywell, J. Le-Rademacher, P. White, Andrew B Dodge, C. Albany, C. Loprinzi   +6 more
semanticscholar   +1 more source

Longitudinal Gut Microbiota Dysbiosis Underlies Olanzapine-Induced Weight Gain

Microbiology Spectrum, 2023
Olanzapine is one of the most effective medicines available for stabilizing schizophrenia spectrum disorders. However, it has been reported to show the greatest propensity for inducing body weight gain and producing metabolic side effects, which cause a ...
Li Qian, Xiaoyan He, Yixin Liu, Fengjie Gao, Wen Lu, Yajuan Fan, Yuan Gao, Wei Wang, Feng Zhu, Yanan Wang, Xiancang Ma   +10 more
doaj   +1 more source

Antipsychotic Treatment Effectiveness in First Episode of Psychosis: PAFIP 3-Year Follow-Up Randomized Clinical Trials Comparing Haloperidol, Olanzapine, Risperidone, Aripiprazole, Quetiapine, and Ziprasidone

International Journal of Neuropsychopharmacology, 2020
Background Different effectiveness profiles among antipsychotics may be a key point to optimize treatment in patients suffering a first episode of psychosis to impact on long-term outcome. The aim of this study is to compare the clinical effectiveness of
M. Gómez-Revuelta, J. Pelayo-Terán, M. Juncal-Ruiz, J. Vázquez-Bourgon, P. Suárez-Pinilla, Rodrigo Romero-Jiménez, Esther Setién Suero, R. Ayesa-Arriola, B. Crespo-Facorro   +8 more
semanticscholar   +1 more source

The Balance Between the Effectiveness and Safety for Chemotherapy-Induced Nausea and Vomiting of Different Doses of Olanzapine (10 mg Versus 5 mg): A Systematic Review and Meta-Analysis

Frontiers in Oncology, 2021
IntroductionThe aim of this study is to rigorously review the efficacy and safety of olanzapine in chemotherapy-induced nausea and vomiting (CINV) settings including (1) at 5- and 10-mg doses, and (2) the setting of highly emetogenic chemotherapy (HEC ...
Dong-Yang Wang, Yi Chen, You Zhang, Ying-Qiang Shen   +3 more
doaj   +1 more source

Efficacy and Safety of a Combination of Olanzapine and Samidorphan in Adult Patients With an Acute Exacerbation of Schizophrenia: Outcomes From the Randomized, Phase 3 ENLIGHTEN-1 Study.

Journal of Clinical Psychiatry, 2020
OBJECTIVE To assess the antipsychotic efficacy and safety of a combination of olanzapine and samidorphan (OLZ/SAM). METHODS This 4-week, phase 3, randomized, double-blind, placebo- and olanzapine-controlled study was conducted from December 2015 to ...
S. Potkin, J. Kunovac, B. Silverman, A. Simmons, Ying Jiang, Lauren DiPetrillo, D. McDonnell   +6 more
semanticscholar   +1 more source

Olanzapine-induced hiccups： a case report

Sichuan jingshen weisheng, 2021
The case report aims to raise the concern of clinicians about hiccups as an adverse reaction in olanzapine treatment. A 47-year-old male patient with epileptic mental disorder appeared symptoms of persistent hiccups on the fourth day of treatment with ...
Sun Zhenxiao, Xu Chunmei, Zhao Lin
doaj   +1 more source