Results 31 to 40 of about 27,607 (170)

Bilateral Basal Ganglion Hemorrhage after Severe Olanzapine Intoxication

Case Reports in Psychiatry, 2020
Olanzapine is a second-generation antipsychotic drug which is generally considered safe with well therapeutic antipsychotic effects. We describe a patient suffering from bilateral intracerebral hemorrhage after severe olanzapine intoxication without ...
Kerstin Schweyer, Bastian Fatke, Kornelia Kreiser, Christian Rabe, Christian Seifert, Benno Ikenberg   +5 more
doaj   +1 more source

Genetic Association of Olanzapine Treatment Response in Han Chinese Schizophrenia Patients

Frontiers in Pharmacology, 2019
Olanzapine, a second-generation antipsychotic medication, plays a critical role in current treatment of schizophrenia (SCZ). It has been observed that the olanzapine responses in schizophrenia treatment are different across individuals.
Wei Zhou, Yong Xu, Qinyu Lv, Yong-hui Sheng, Luan Chen, Mo Li, Lu Shen, Cong Huai, Zhenghui Yi, Donghong Cui, Donghong Cui, Shengying Qin, Shengying Qin   +12 more
doaj   +1 more source

Hyperbaric oxygen exposure alleviate metabolic side-effects of olanzapine treatment and is associated with Langerhans islet proliferation in rats

Pathology and Oncology Research, 2022
Introduction: Olanzapine (OLZ) is one of the second-generation antipsychotics drugs (APDs) used to treat several psychiatric illnesses. Olanzapine treatment is often associated with many metabolic side effects in a dose dependent manner such as obesity ...
Mohammad AlQudah, Mohammad Khalifeh, Rasha Al-Azaizeh, Amr Masaadeh, Amr Masaadeh, Omar M. Al-Rusan, Omar M. Al-Rusan, Husam K. Haddad   +7 more
doaj   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations

Clinical Pharmacology &Therapeutics, EarlyView.
Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar, Natasha Monte da Silva, Juliana Carla Gomes Rodrigues, André Maurício Ribeiro‐dos‐Santos, Sandro José de Souza, Ândrea Ribeiro‐dos‐Santos, João Farias Guerreiro, Sidney Emanuel Batista dos Santos, Marianne Rodrigues Fernandes, Ney Pereira Carneiro dos Santos   +9 more
wiley   +1 more source

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

Peripheral edema due to olanzapine use: a case report

Psychiatry and Behavioral Sciences, 2016
Peripheral edema is associated with multiple medical etiologies (systemic disorders, hypoproteinemia, long-term immobility, cancer diseases) and drugs (nonsteroidal anti-inflammatory drugs, antihypertensives, steroids, and immunsupressive agents ...
Musa Şahpolat, Umit Sertan Copoğlu, Mehmet Hanifi Kokacya   +2 more
doaj   +1 more source

Attenuation of Olanzapine-Induced Endoplasmic Reticulum Stress Improves Insulin Secretion in Pancreatic Beta Cells

Metabolites, 2022
Second-generation antipsychotics (SGAs), in particular, olanzapine and clozapine, have been associated with the development of type 2 diabetes mellitus (T2D) and metabolic syndrome in individuals with schizophrenia. In this context, beta cell dysfunction
Diana Grajales, Patricia Vázquez, Rosa Alén, Ana B. Hitos, Ángela M. Valverde   +4 more
doaj   +1 more source

Olanzapine Overdose in a Pin Point Pupil with Altered Sensorium [PDF]

Asia Pacific Journal of Medical Toxicology, 2017
Background:Olanzapine is a highly tolerable and easily affordable atypical antipsychotic drug which has been commonly prescribed in both inpatient and outpatient settings for several mental disorders.
Naresh Midha, Arup Misra, Vivek Chhabra, Gopal Bohra   +3 more
doaj   +1 more source

Guidelines for nutrition in adults with head and neck cancer: The American Society for Parenteral and Enteral Nutrition

Journal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Background Head and neck cancer represents the seventh most common cancer diagnosis globally. Maintaining sufficient nutrition is important for preventing malnutrition (undernutrition) and muscle wasting, which contribute to worse outcomes, although many patients are unable to maintain adequate oral intake throughout treatment.
Nicole Kiss, Merran Findlay, Jacqui Frowen, Whitney E. Lewis, Jeannine Mills, Anurag K. Singh, David D. Church, Jacob T. Mey, Sarah Peterson, Kathleen Aguzzi, Sarah Bellini, Maria Paula Villela Coelho, Laura Cordwin, Michael Duffy, Shanna Hager, Manpreet S. Mundi, Michael Owen‐Michaane, Kathleen Price, Heather Stanner, Bridget Storm, Malika Udagedara, Liam McKeever   +21 more
wiley   +1 more source