Results 171 to 180 of about 25,067 (205)

Absence of synergistic effects by CDK12/13 inhibition in combination with cisplatin or olaparib in ovarian cancer cells. [PDF]

open access: yesSci Rep
Santer FR   +10 more
europepmc   +1 more source

Cleavage and inactivation of poly(ADP-ribose) polymerase in peripheral blood mononuclear cells of patients with acute respiratory distress syndrome. [PDF]

open access: yesRespir Res
Santos SS   +13 more
europepmc   +1 more source

Olaparib

Reactions Weekly, 2018
Olaparib (Lynparza [AstraZeneca, Cambridge, UK], formerly referred to as AZD2281 or KU0059436) is an oral poly(ADP-ribose) polymerase (PARP) inhibitor. It is rationally designed to act as a competitive inhibitor of NAD+ at the catalytic site of PARP1 and PARP2, both members of the PARP family of enzymes that are central to the repair of DNA single ...
Sylvia, Bochum   +2 more
  +6 more sources

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