Results 201 to 210 of about 41,944 (264)

Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death [PDF]

, 2019
al., et, Ellenberger, Tom, Houl, Jerry H., Kim, In-Kwon, Stegeman, Roderick A.   +4 more
core   +1 more source

Micronucleus quantification from whole-slide haematology images using AI serves as a translatable pharmacodynamic biomarker for DNA damage response inhibitors. [PDF]

Sci Rep
Yong KHR, Robak WS, Mulderrig L, Hughes A, Bystry R, Wantenaar T, Jones GN, Udriste M, Robertson J, Forment JV, O'Connor LO, Hill RJ.   +11 more
europepmc   +1 more source

Drastic Response to Olaparib in a Patient With Metastatic Castration-Resistant Prostate Cancer Harboring BRCA2 Alterations and Near-Threshold Tumor Mutational Burden. [PDF]

IJU Case Rep
Yokota K, Kosaka T, Daimon T, Fujiwara S, Nakamura K, Nishihara H, Oya M.   +6 more
europepmc   +1 more source

Olaparib monotherapy in patients with advanced cancer and a germline BRCA1/2 mutation.

Journal of Clinical Oncology, 2015
B. Kaufman, R. Shapira-Frommer, Rita K Schmutzler, M. Audeh, M. Friedlander, J. Balmaña, G. Mitchell, G. Fried, Salomon M. Stemmer, A. Hubert, O. Rosengarten, M. Steiner, N. Loman, K. Bowen, A. Fielding, S. Domchek   +15 more
semanticscholar   +1 more source

Durable complete radiographic and biochemical response to olaparib in BRCA2-mutated metastatic castration-resistant prostate cancer: a long-term responder case. [PDF]

Urol Case Rep
Ito F, Kobayashi K, Hayashi G, Kamijo S, Fujita T.   +4 more
europepmc   +1 more source

Curcumin induces and enhances the PARP1-mediated parthanatos in diffuse large B cell lymphoma. [PDF]

Oncol Lett
Wang Y, Qi R, Zhao X, Mei H, Qiu M, Liu F, Wang H.   +6 more
europepmc   +1 more source

CircRNA14781 promotes olaparib resistance of ovarian cancer cells by regulating miR-330-5p/NGFR pathway. [PDF]

J Ovarian Res
Chen B, Zong S, Tang J, Wang H, Lu X, Wang J, Jia X.   +6 more
europepmc   +1 more source

MOB2 Loss Sensitizes Lung Cancer Cells to PARP Inhibition Through p53-Dependent DNA Damage Signaling. [PDF]

Curr Issues Mol Biol
Gundogdu R.
europepmc   +1 more source

Efficacy and safety of PARP inhibitors monotherapy or combination therapy with anti-angiogenics in ovarian cancer: a network meta-analysis. [PDF]

Front Oncol
Liu Y, Ren T, Wang X, Wang Y, Tang L, Cao W.   +5 more
europepmc   +1 more source