Results 81 to 90 of about 301,945 (302)

Assessing the vulnerability and conservation potential of old‐growth forests in British Columbia, Canada

open access: yesEcosphere
Climate change is predicted to have widespread effects on the distribution of many species and ecosystems, including old‐growth forests. Because of the slow development time of old‐growth forests, it is especially important for their management to map ...
Nick Pochailo   +4 more
doaj   +1 more source

Smallholder agriculture results in stable forest cover in riverine Amazonia

open access: yesEnvironmental Research Letters, 2021
Recent studies point to a rapid increase in small-scale deforestation in Amazonia. Where people live along the rivers of the basin, customary shifting cultivation creates a zone of secondary forest, orchards and crop fields around communities in what was
Oliver T Coomes   +4 more
doaj   +1 more source

Effects of management practices on water yield in small headwater catchments at Cordillera de los Andes in southern Chile [PDF]

open access: yes, 2009
In several parts of the world, drinking water is obtained from springs in natural and managed mountainous forests. Since forests regulate quality as well as quantity of water, the effects of forest-management activities on water yield are an important ...
Godoy, Roberto   +3 more
core  

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

open access: yesAdvanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li   +22 more
wiley   +1 more source

Deadwood Diversity of Boreal and Sub-boreal Old-growth Forests in Southern Finland

open access: yesSouth-East European Forestry
In the last century, old-growth forests in boreal and sub-boreal zone have decreased, along with their contribution to biological diversity. In order to carry on management strategies aimed at maintaining deadwood diversity in old-growth forests, it is ...
Isabella De Meo   +3 more
doaj   +1 more source

Does restoration success vary with tree size under restoration plantings and regrowth forests?

open access: yesConservation Science and Practice, 2022
Several studies evaluate active (i.e., seeding/planting) and passive (i.e., protecting forest regrowth) restoration, but few studies examine successional patterns for different plant sizes.
Enock Ssekuubwa   +7 more
doaj   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

open access: yesAdvanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu   +15 more
wiley   +1 more source

Cuproptosis and Mitophagy Mediated by the THUMPD1/IGF2R‐Dependent Suppression of AKT and Activation of AMPK Signaling Suppress Lung Adenocarcinoma Progression

open access: yesAdvanced Science, EarlyView.
THUMPD1 drives a tumor‐suppressive signaling cascade in lung adenocarcinoma by promoting IGF2R expression. IGF2R associates with PPP2R1A to suppress AKT and activate AMPK, leading to SLC31A1 upregulation and copper accumulation. Elevated copper disrupts mitochondrial metabolism and induces excessive mitophagy, thereby restraining tumor growth and ...
Kai Wu   +10 more
wiley   +1 more source

Dispersal ecology of the endangered woodland lichen Lobaria pulmonaria in managed hemiboreal forest landscape [PDF]

open access: yes, 2018
Changes in the forest management practices have strongly influenced the distribution of species inhabiting old-growth forests. The epiphytic woodland lichen Lobaria pulmonaria is frequently used as a model species to study the factors affecting the ...
Adolf, Carole   +6 more
core  

A Nanobody‐LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Plastin‐2 (PLS2) is identified as a dual‐function receptor on DCs that mediates both nanoparticle uptake and immunomodulation. A nanobody‐LNP platform is engineered to integrate antigen delivery with relicensing DCs. The therapeutic strategy elicits potent anti‐tumor T cell responses and leads to significant inhibition of established tumors in vivo ...
Shugang Qin   +9 more
wiley   +1 more source

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