Results 101 to 110 of about 17,456,883 (336)

Old Age

open access: yesNature, 1904
Growing up from elementary to the adult, reading books will let different reasons to believe. Sometime, we need the book because of the job deadline.
C. Baker
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Moderating effects of gender, age and cognitive reserve on combined cognitive training and transcranial electrical stimulation

open access: yesBrain Stimulation, 2023
Christine Krebs   +4 more
doaj   +1 more source

No Effect of Anodal tDCS on Verbal Episodic Memory Performance and Neurotransmitter Levels in Young and Elderly Participants

open access: yesNeural Plasticity, 2020
Healthy ageing is accompanied by cognitive decline that affects episodic memory processes in particular. Studies showed that anodal transcranial direct current stimulation (tDCS) to the left dorsolateral prefrontal cortex (DLPFC) may counteract this ...
Annegret Habich   +4 more
doaj   +1 more source

The Age of the Universe [PDF]

open access: yes, 1998
A minimum age of the universe can be estimated directly by determining the age of the oldest objects in the our Galaxy. These objects are the metal-poor stars in the halo of the Milky Way.
Chaboyer, Brian
core   +3 more sources

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

MADRS single items differential changes among patients with melancholic and unspecified depression treated with ECT: an exploratory study

open access: yesFrontiers in Psychiatry
IntroductionMajor depressive disorder (MDD) exhibits heterogeneity in treatment response.ObjectiveThis exploratory analysis aims to evaluate the differential changes in individual items of the MADRS between melancholic MDD (M-MDD) and unspecified MDD (U ...
Beatriz Pozuelo Moyano   +6 more
doaj   +1 more source

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