Results 71 to 80 of about 17,456,883 (336)

Drinking Behaviors and Health in Old Age [PDF]

open access: yes, 2018
Alcohol abuse among the elderly population is rapidly becoming a widespread public health concern. As it goes undetected and undiagnosed in many within this age cohort, there is an increased need to further examine the effects of alcohol consumption on ...
Knapp, Kaleigh
core   +1 more source

Targeting senescent cells enhances adipogenesis and metabolic function in old age

open access: yeseLife, 2015
Senescent cells accumulate in fat with aging. We previously found genetic clearance of senescent cells from progeroid INK-ATTAC mice prevents lipodystrophy.
Ming Xu   +13 more
semanticscholar   +1 more source

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

Has Anyone Ever Died of Old Age? [PDF]

open access: yes, 2003
The omission of aging as a legal cause of death and the largely unrecognized contribution the aging process plays in mortality is ...
Harry R. Moody, Loeonard Hayflick
core  

A Robust Age Indicator for Old Stellar Populations

open access: yes, 1999
We derive new spectral H_gamma index definitions which are robust age indicators for old and relatively old stellar populations and thus have great potential for solving the age-metallicity degeneracy of galaxy spectra.
A. Vazdekis   +7 more
core   +2 more sources

The impact of obesity on skeletal muscle strength and structure through adolescence to old age

open access: yesBiogerontology (Dordrecht), 2015
Obesity is associated with functional limitations in muscle performance and increased likelihood of developing a functional disability such as mobility, strength, postural and dynamic balance limitations.
D. Tomlinson   +5 more
semanticscholar   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Midlife hand grip strength as a predictor of old age disability.

open access: yesJournal of the American Medical Association (JAMA), 1999
CONTEXT Poor muscle strength, functional limitations, and disability often coexist, but whether muscle strength during midlife predicts old age functional ability is not known.
T. Rantanen   +6 more
semanticscholar   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

Pathways and Patterns of Cell Loss in Verified Alzheimer’s Disease: A Factor and Cluster Analysis of Clinico-Pathological Subgroups

open access: yesBehavioural Neurology, 1994
Thirty-seven patients with neuropathologically verified Alzheimer's disease (AD) have been studied prospectively. A principal components analysis of neuron numbers in cortical and subcortical areas revealed two variables: Variable I with high loadings ...
H. Förstl   +4 more
doaj   +1 more source

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