Results 131 to 140 of about 3,409,145 (305)
Community Response Grids for Older Adults: Motivations, Usability, and Sociability
, 2008 This paper discusses the motivation for a Community Response Grid (CRG) to help older adults improve their capability for coping with emergency situations.
Ben Shneiderman +6 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
The learning needs of older adults
, 2003 The capacity of older adults to remain physically, mentally, and socially active is partly dependent on continued participation in learning and education. Older\ud adults, however, often are not considered as likely candidates for learning.
Boulton-Lewis, Gillian M. +1 more
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Health Promotion for Older Adults: What Is the Potential? 11th Annual Herbert Lourie Memorial Lecture on Health Policy [PDF]
As a greater number of people reach old age, medicine is challenged to develop new approaches to this population. Health promotion, not just treatment of disease but improving the quality of life for older persons, must play a role.
Linda P. Fried
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FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Investigating User Authentication in the Context of Older Adults [PDF]
Knowledge-based authentication is almost ubiquitous due to low cost and relatively straightforward implementation. Despite its popularity, there are some well-known problems associated with knowledge-based authentication, such as the cognitive load of ...
Nicholson, James
core
Patient Preference and Adherence, 2019 Huey-Ming Tzeng,1 Udoka Okpalauwaekwe,2 Chang-Yi Yin3 1College of Nursing, University of Saskatchewan, Saskatoon, SK, Canada; 2Department of Academic Family Medicine, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada; 3Taiwan ...
Tzeng HM, Okpalauwaekwe U, Yin CY
doaj
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source