Results 91 to 100 of about 1,236,036 (312)
Possible Effects of the Financial Crisis on Managers’ Attitudes to Older Workers
Nordic Journal of Working Life Studies, 2012 The article explores the possible short-term effects of the financial crisis in Norway on cognitive, affective, and behavioral components of managers’ attitudes to older workers.
Per Erik Solem
doaj +1 more source
Older Male Workers and Job Mobility in Australia [PDF]
Extending the working life of older workers has been identified as an important policy goal in the context of an ageing society. However, existing research has highlighted the role of job separation and labour force discouragement for older worker labour
O'Brien, Martin
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Retaining through Training: Even for Older Workers [PDF]
This paper investigates whether on-the-job training has an effect on the employability of workers. Using data from the Netherlands we disentangle the true effect of training incidence from the spurious one determined by unobserved individual ...
Picchio, Matteo, van Ours, Jan C.
core +3 more sources
Unemployment Compensation and Older Workers [PDF]
Unemployment compensation in the United States is provided through a federal-state system of unemployment insurance (UI). UI provides temporary partial wage replacement to active job seekers who are involuntarily out of work.
Christopher J. O'Leary +1 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Discouraged Workers? Job Search Outcomes of Older Workers [PDF]
Many have suggested we adopt policies that explicitly encourage the elderly to work. Behind this suggestion is the assumption that if an older person desires a job, one will be found; however, little is known about the extent to which this is true, and ...
Nicole Maestas, Xiaoyan Li
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Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Age and opportunities for promotion [PDF]
Using a panel of new firms and their employees, this paper studies the promotion opportunities for older workers within the same firm. Survival analysis suggests that younger employees experience shorter times to promotion than older workers and ...
C. Sofia Machado, Miguel Portela
core
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source