Results 91 to 100 of about 2,288 (247)

Streptavidins Coordinate Biotin Sequestration and Self‐Resistance Within a Biotin‐Pathway Antibiotic Network

Advanced Science, EarlyView.
A conserved genomic region between two streptavidin genes in Streptomyces packages biosynthetic gene clusters for diverse biotin‐pathway antibiotics: acidomycin, stravidin, the new non‐proteinogenic amino acid ANDA, and the new BioA inhibitor α‐methyl‐KAPA.
Sumire Kurosawa, Jingjun Mo, Xiaotong Diao, Feng Xie, Tingting Wang, Haowen Zhao, Dalei Wu, Rolf Müller, Chengzhang Fu   +8 more
wiley   +1 more source

Bioconversion of agro-industrial carbon wastes into biodiesel feedstocks with superior fuel properties by promising oleaginous yeasts and cultivation strategies

Carbon Resources Conversion
Oleaginous yeasts hold significant potential as biodiesel feedstocks as they accumulate high content of lipids with similar fatty acid profiles to those of plant oils.
Amporn Malisorn, Benjamas Cheirsilp, Asma Billateh, Yasmi Louhasakul, Apichat Upaichit   +4 more
doaj   +1 more source

Genome-wide functional screens enable the prediction of high activity CRISPR-Cas9 and -Cas12a guides in Yarrowia lipolytica

Nature Communications, 2022
The successful use of CRISPR-based mutagenesis in non-conventional microorganisms requires high activity sgRNAs. Here, the authors present DeepGuide, a neural network-based architecture, that learns from genome-wide CRISPR activity profiles to accurately
Dipankar Baisya, Adithya Ramesh, Cory Schwartz, Stefano Lonardi, Ian Wheeldon   +4 more
doaj   +1 more source

Oil production on wastewaters after butanol fermentation by oleaginous yeast Trichosporon coremiiforme

, 2012
From the distillation process after butanol fermentation, wastewaters mainly consisted of organic acids and residual sugars and with high COD (usually >20,000 mg/L) are generated. Without any pretreatment and adding other nutrients (nitrogen sources
Ma, Long-long, Huang, Chao, Chen, Xue-fang, Chen, Xin-de, Xiong, Lian, Chen, Yong   +5 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Palms make way for oleaginous yeast [PDF]

Nature Reviews Chemistry, 2019
Oleaginous yeasts grown on biomass sustainably produce high yields of triglycerides for use in foods and fuels.
openaire   +1 more source

A Cationic Supramolecule With Potent Antifungal Activity, Single‐Species Selectivity, and Strong Synergy With Echinocandins

Advanced Science, EarlyView.
We introduce a new membrane‐active antifungal design, Gua‐SMACS‐16, that exhibits high potency and single‐species selectivity for C. tropicalis while sparing other close species in the Candida genus. Moreover, when combining with caspofungin, a clinical antifungal drug inhibiting 1,3‐β‐glucan synthase, they exhibit ultra‐strong synergy across a panel ...
Tianjiao Dai, Adrielle Xianwen Chen, Eve Wai Ling Chow, Li Mei Pang, Jianguo Li, Chandra Shekhar Verma, Stefan H. Oehlers, Yue Wang, Ning Li   +8 more
wiley   +1 more source

Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity

Advanced Science, EarlyView.
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao, Wei Liu, Xiuping Liang, Jie Bai, Hong Chang, Wenchao Chen, Mohamed A. Farag, Jianbo Xiao, Huifeng Jiang, Jiasheng Wu, Lili Song   +10 more
wiley   +1 more source

Trans-omic analysis of the oleaginous yeast Rhodosporidium toruloides

, 2012
Trans-omic analysis of the oleaginous yeast Rhodosporidium ...
赵宗保, 朱志伟, 张素芳, 刘宏伟, 邹汉法   +4 more
core  

Modeling growth, lipid accumulation and lipid turnover in submerged batch cultures of Umbelopsis isabellina [PDF]

, 2011
The production of lipids by oleaginous yeast and fungi becomes more important because these lipids can be used for biodiesel production. To understand the process of lipid production better, we developed a model for growth, lipid production and lipid ...
Meeuwse, P., Tramper, J., Arjen Rinzema, Akbari, P., Payman Akbari, Johannes Tramper, Rinzema, A., Petra Meeuwse   +7 more
core   +1 more source