Results 91 to 100 of about 409,832 (264)

Neurogenesis Drives Stimulus Decorrelation in a Model of the Olfactory Bulb [PDF]

, 2012
The reshaping and decorrelation of similar activity patterns by neuronal networks can enhance their discriminability, storage, and retrieval. How can such networks learn to decorrelate new complex patterns, as they arise in the olfactory system?
A Arevian, A Fantana, A Mouret, A Mouret, A Sahay, AM McNamara, B Johnson, B Winner, Boris S. Gutkin, C Linster, C Rochefort, CW Lin, D Chaudhury, D Rinberg, D Wilson, DA Wilson, DJ Heeger, E Yaksi, F David, F Kermen, F Lazarini, F Lazarini, GA Cecchi, GK Mak, GK Mak, GM Shepherd, Hermann Riecke, I Imayoshi, I Ortega-Perez, J Ninkovic, JT Davie, L Belnoue, L Petreanu, LM Kay, M Alonso, M Satou, M Valley, M Whitman, M Yamaguchi, MC Whitman, MD Döbrössy, MM Moreno, MT Wiechert, N Kaneko, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Mandairon, N Miwa, O Escanilla, P Panzanelli, PA Brennan, PE Castillo, PM Lledo, Q Nai, R Pressler, RE Dolmetsch, RW Friedrich, RW Friedrich, S Sultan, S Sultan, S Sultan, S Wick, Siu-Fai Chow, SR Olsen, SS Magavi, Stuart D. Wick, SW Kuffler, SX Luo, T Shingo, TA Cleland, TA Cleland, TB Woolf, TK Yokoyama, V Breton-Provencher, V Egger, V Egger, W Kelsch, W Kim, Y Gao   +81 more
core   +6 more sources

Olfactory Neuroblastoma [PDF]

Head and Neck Pathology, 2006
Few neoplasms are unique to the sinonasal tract, but sinonasal undifferentiated carcinoma and olfactory neuroblastoma are malignant tumors which require unique management. Due to the rarity of these tumors, practicing pathologists are not always aware of their distinctive clinical, radiographic, histologic, immunohistochemical, and molecular features ...
openaire   +4 more sources

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

An Alzheimer’s Disease Patient-Derived Olfactory Stem Cell Model Identifies Gene Expression Changes Associated with Cognition [PDF]

, 2022
Laura M. Rantanen, Mainá Bitar, Riikka Lampinen, Romal Stewart, Hazel Quek, Lotta E. Oikari, Carla Cuní‐López, Ratneswary Sutharsan, Gayathri Thillaiyampalam, Jamila Iqbal, Daniel Russell, Elina Penttilä, Heikki Löppönen, Juha-Matti Lehtola, Toni Saari, Sanna Hannonen, Anne M. Koivisto, Larisa M. Haupt, Alan Mackay‐Sim, Alexandre S. Cristino, Katja M. Kanninen, Anthony R. White   +21 more
openalex   +1 more source

Gut Microbiota‐Derived Anandamide Mediates the Therapeutic Effects of Urolithin A on Alcohol‐Induced Cognitive and Social Dysfunction via CB1R‐DRD2‐RAP1 Signaling Axis

Advanced Science, EarlyView.
This study reveals that Urolithin A (UA) counteracts alcohol‐induced cognitive and social dysfunction (AICSD) via a gut microbiome‐dependent mechanism. UA‐enriched Bacteroids sartorii and Parabacteroids distasonis elevate anandamide (AEA), which activates the CB1R‐DRD2‐Rap1 signaling cascade to drive synaptic repair and reduce neuroinflammation ...
Hongbo Zhang, Zibin Li, Yao Xiao, Ji Bian, Caian He, Chao Liu, Lan Gong, Lin Han, Zhigang Liu, Min Wang   +9 more
wiley   +1 more source

Correlational patterns of neuronal activation and epigenetic marks in the basolateral amygdala and piriform cortex following olfactory threat conditioning and extinction in rats

Frontiers in Molecular Neuroscience
IntroductionCumulative evidence suggests that sensory cortices interact with the basolateral amygdala (BLA) defense circuitry to mediate threat conditioning, memory retrieval, and extinction learning.
Tian Qin, Yue Xia, Negar Nazari, Tayebeh Sepahvand, Qi Yuan   +4 more
doaj   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Pollen elicits proboscis extension but does not reinforce PER learning in honeybees [PDF]

, 2013
The function of pollen as a reward for foraging bees is little understood, though there is evidence to suggest that it can reinforce associations with visual and olfactory floral cues.
Casteel, Erber, Goodman, Hammer, Hardin, Levin, Menzel, Menzel, Robertson, Roulston, Schmidt   +10 more
core   +2 more sources

Discovery of a Novel and Potent Kir4.1 Inhibitor as a Safe and Rapid‐Onset Antidepressant Agent in Mice

Advanced Science, EarlyView.
The preferred derivative JX3212 demonstrates strong inhibitory activity against Kir4.1 with favorable druggability and shows significant antidepressant efficacy in vivo. Abstract Major depressive disorder is a serious psychiatric disorder for which novel and fast‐acting antidepressants are required.
Sisi Wang, Xiaoyu Zhou, Mengdan Li, Chao Zhang, Haiyan Xu, Jingyi He, Li Zhan, Yueling Gu, Hao Gu, Tianyu Tu, Hanfang Liu, Taotao Lu, Yueming Zheng, Jian Li, Zhaobing Gao, Yixiang Xu   +15 more
wiley   +1 more source

Visual-, Olfactory-, and Nectar-Taste-Based Flower Aposematism

Plants
Florivory, i.e., flower herbivory, of various types is common and can strongly reduce plant fitness. Flowers suffer two very different types of herbivory: (1) the classic herbivory of consuming tissues and (2) nectar theft.
Simcha Lev-Yadun
doaj   +1 more source