Results 21 to 30 of about 468,211 (358)

Olfactory Neuroblastoma [PDF]

Cancer, 1989
Fifteen patients with olfactory neuroblastoma were treated during the 17-year period of 1969 to 1986. Data was analyzed with respect to age at presentation, sex, presenting signs and symptoms, stage, and results of treatment. Age ranged from 4 to 67 years with the median age being 27 years. Median follow-up was 8 years.
T A, O'Connor, P, McLean, G J, Juillard, R G, Parker   +3 more
openaire   +2 more sources

Expression of the SARS-CoV-2 Entry Proteins, ACE2 and TMPRSS2, in Cells of the Olfactory Epithelium: Identification of Cell Types and Trends with Age

ACS Chemical Neuroscience, 2020
The COVID-19 pandemic revealed that there is a loss of smell in many patients, including in infected but otherwise asymptomatic individuals. The underlying mechanisms for the olfactory symptoms are unclear.
Katarzyna Bilińska, Patrycja Jakubowska, C. V. von Bartheld, R. Butowt   +3 more
semanticscholar   +1 more source

Efficacy and safety of oral corticosteroids and olfactory training in the management of COVID-19-related loss of smell

European Archives of Oto-Rhino-Laryngology, 2021
Purpose As the COVID-19 pandemic continues, an increasing number of patients are afflicted by olfactory loss, a now well-recognized symptom of the disease.
S. L. Le Bon, D. Konopnicki, Nathalie Pisarski, L. Prunier, Jérôme R. Lechien, M. Horoi   +5 more
semanticscholar   +1 more source

Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb [PDF]

, 2017
Background Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs.
Caretta, Antonio, Mucignat, Carla
core   +2 more sources

Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]

, 1993
The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer, Bergmann, Betz, Bixby, Breipohl, Brunjes, Elferink, Farbman, Farbman, Fletcher, Geppert, Gesteland, Graziadei, Halász, Halász, Hinds, Hsu, Huttner, Jahn, Jahn, Knaus, Kosaka, Lahr, Lahr, Leube, Mandell, Marchand, Margolis, Marquèze-Pouey, Matteoli, McLean, Navone, Ovtscharoff, Pedersen, Rehn, Schwob, Schwob, Shipley, Smotherman, Specht, Specht, Südhof, Thomas, Thomas, Tixier-Vidal, Trimble, Van Lookeren Campagne, Verhaagen, Wendland, Wiedenmann, Zhong   +50 more
core   +1 more source

Opposite regulation of inhibition by adult-born granule cells during implicit versus explicit olfactory learning

eLife, 2018
Both passive exposure and active learning through reinforcement enhance fine sensory discrimination abilities. In the olfactory system, this enhancement is thought to occur partially through the integration of adult-born inhibitory interneurons resulting
Nathalie Mandairon, Nicola Kuczewski, Florence Kermen, Jérémy Forest, Maellie Midroit, Marion Richard, Marc Thevenet, Joelle Sacquet, Christiane Linster, Anne Didier   +9 more
doaj   +1 more source

Rapid odor processing by layer 2 subcircuits in lateral entorhinal cortex

eLife, 2022
Olfactory information is encoded in lateral entorhinal cortex (LEC) by two classes of layer 2 (L2) principal neurons: fan and pyramidal cells. However, the functional properties of L2 cells and how they contribute to odor coding are unclear.
Sebastian H Bitzenhofer, Elena A Westeinde, Han-Xiong Bear Zhang, Jeffry S Isaacson   +3 more
doaj   +1 more source

Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia

Science Advances, 2020
: Altered olfactory function is a common symptom of COVID-19, but its etiology is unknown. A key question is whether SARS-CoV-2 (CoV-2) – the causal agent in COVID-19 – affects olfaction directly, by infecting olfactory sensory neurons or their targets ...
D. Brann, Tatsuya Tsukahara, Caleb Weinreb, M. Lipovsek, Koen Van den Berge, Boying Gong, Rebecca K. Chance, Iain C. Macaulay, Hsin-Jung Chou, Russell B. Fletcher, D. Das, Kelly Street, Hector Roux de Bézieux, Yoon-Gi Choi, D. Risso, S. Dudoit, E. Purdom, J. Mill, R. Hachem, Hiroaki Matsunami, Darren W. Logan, Bradley J. Goldstein, M. Grubb, J. Ngai, S. R. Datta   +24 more
semanticscholar   +1 more source

Massive transient damage of the olfactory epithelium associated with infection of sustentacular cells by SARS-CoV-2 in golden Syrian hamsters

bioRxiv, 2020
Anosmia is one of the most prevalent symptoms of SARS-CoV-2 infection during the COVID-19 pandemic. However, the cellular mechanism behind the sudden loss of smell has not yet been investigated.
Bertrand Bryche, Audrey St Albin, S. Murri, Sandra Lacôte, C. Pulido, Meriadeg Ar Gouilh, S. Lesellier, A. Servat, M. Wasniewski, E. Picard-Meyer, E. Monchatre-Leroy, R. Volmer, O. Rampin, R. Le Goffic, P. Marianneau, N. Meunier   +15 more
semanticscholar   +1 more source

Short-term availability of adult-born neurons for memory encoding

Nature Communications, 2019
Olfactory bulb neurogenesis raises the question of how persistent olfactory memories are retained while remaining flexible to encode new memories. Here, the authors show that new neurons can only support a single odor memory within their critical period ...
Jérémy Forest, Mélissa Moreno, Matthias Cavelius, Laura Chalençon, Anne Ziessel, Joëlle Sacquet, Marion Richard, Anne Didier, Nathalie Mandairon   +8 more
doaj   +1 more source