Massive normalization of olfactory bulb output in mice with a 'monoclonal nose' [PDF]
eLife, 2016 Perturbations in neural circuits can provide mechanistic understanding of the neural correlates of behavior. In M71 transgenic mice with a “monoclonal nose”, glomerular input patterns in the olfactory bulb are massively perturbed and olfactory behaviors ...
Benjamin Roland +8 more
doaj +3 more sources
Neuroanatomical Reflections of Childhood Obesity: Volumetric Analysis of the Pituitary Gland and Olfactory Bulb [PDF]
ChildrenIntroduction: Obesity is a rapidly increasing condition that leads to serious health issues. The sense of smell, one of the oldest senses related to energy metabolism, has been increasingly studied in relation to obesity.
Emel Hatun Aytaç Kaplan +4 more
doaj +2 more sources
High-fat diet triggers transcriptomic changes in the olfactory bulb [PDF]
HeliyonMetabolic imbalance contributes to cognitive impairment, anxiety, depressive behavior, and impaired olfactory perception. Recent studies have focused on olfactory dysfunction in patients with obesity and diabetes accompanied by cognitive dysfunction ...
Young-Kook Kim +3 more
doaj +2 more sources
The olfactory bulb as the entry site for prion-like propagation in neurodegenerative diseases
Neurobiology of Disease, 2018 Olfactory deficits are present in numerous neurodegenerative disorders and are accompanied by pathology in related brain regions. In several of these disorders, olfactory disturbances appear early and are considered as prodromal symptoms of the disease ...
Nolwen L Rey +2 more
exaly +3 more sources
Brazilian Journal of Otorhinolaryngology, 2022 Introduction: After total laryngectomy, decreased olfactory function and olfactory bulb volume shrinkage have been reported to occur due to olfactory deprivation caused by nasal airflow interruption.
Defne Gürbüz +3 more
doaj +1 more source
The source of spontaneous activity in the main olfactory bulb of the rat. [PDF]
PLoS ONE, 2011 In vivo, most neurons in the main olfactory bulb exhibit robust spontaneous activity. This paper tests the hypothesis that spontaneous activity in olfactory receptor neurons drives much of the spontaneous activity in mitral and tufted cells via ...
Josif Stakic +3 more
doaj +1 more source
The effect of type 2 diabetes on the olfactory bulb structure of Wistar rats [PDF]
یافتههای نوین در علوم زیستی, 2023 Olfaction, the sense of smell, plays an important role in the individual's safety, nutrition, social interactions, sexual function, and quality of life. Diabetes mellitus, which affects more than 400 million people worldwide, is associated with olfactory
Hamidreza Yahyaeipour +3 more
doaj
Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation. [PDF]
, 2020 In Parkinson's disease, some of the first alpha-synuclein aggregates appear in the olfactory system and the dorsal motor nucleus of the vagus nerve before spreading to connected brain regions.
Brundin, Patrik +3 more
core +2 more sources
Assessment of olfactory nerve by SPECT-MRI image with nasal thallium-201 administration in patients with olfactory impairments in comparison to healthy volunteers. [PDF]
PLoS ONE, 2013 PURPOSE: The aim of this study was to assess whether migration of thallium-201 ((201)Tl) to the olfactory bulb were reduced in patients with olfactory impairments in comparison to healthy volunteers after nasal administration of (201)Tl.
Hideaki Shiga +12 more
doaj +1 more source
环境与职业医学, 2023 BackgroundAir pollution is related to the occurrence and development of mental diseases. Olfactory bulb damage might be the potential prodromal symptom and sign of these diseases.
Yingying JIANG +4 more
doaj +1 more source