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Neuronal organization of olfactory bulb circuits
Olfactory sensory neurons extend their axons solely to the olfactory bulb, which is dedicated to odor information processing. The olfactory bulb is divided into multiple layers, with different types of neurons found in each of the layers.
Fumiaki Imamura, Ching-yu Cheng
exaly +4 more sources
Subpopulations of Projection Neurons in the Olfactory Bulb
Generation of neuronal diversity is a biological strategy widely used in the brain to process complex information. The olfactory bulb is the first relay station of olfactory information in the vertebrate central nervous system.
Fumiaki Imamura+2 more
doaj +2 more sources
Massive normalization of olfactory bulb output in mice with a 'monoclonal nose' [PDF]
Perturbations in neural circuits can provide mechanistic understanding of the neural correlates of behavior. In M71 transgenic mice with a “monoclonal nose”, glomerular input patterns in the olfactory bulb are massively perturbed and olfactory behaviors ...
Benjamin Roland+8 more
doaj +3 more sources
Microplastics in the Olfactory Bulb of the Human Brain.
Key Points Question Can microplastics reach the olfactory bulb in the human brain? Findings This case series analyzed the olfactory bulbs of 15 deceased individuals via micro-Fourier transform infrared spectroscopy and detected the presence of ...
Amato-Lourenço LF+10 more
europepmc +2 more sources
High-fat diet triggers transcriptomic changes in the olfactory bulb [PDF]
Metabolic imbalance contributes to cognitive impairment, anxiety, depressive behavior, and impaired olfactory perception. Recent studies have focused on olfactory dysfunction in patients with obesity and diabetes accompanied by cognitive dysfunction ...
Young-Kook Kim+3 more
doaj +2 more sources
Neurogenesis dynamics in the olfactory bulb: deciphering circuitry organization, function, and adaptive plasticity [PDF]
Adult neurogenesis persists after birth in the subventricular zone, with new neurons migrating to the granule cell layer and glomerular layers of the olfactory bulb, where they integrate into existing circuitry as inhibitory interneurons.
Moawiah M. Naffaa
doaj +2 more sources
Olfactory bulb anomalies in KBG syndrome mouse model and patients [PDF]
ANKRD11 (ankyrin repeat domain 11) is a chromatin regulator and the only gene associated with KBG syndrome, a rare neurodevelopmental disorder. We have previously shown that Ankrd11 regulates murine embryonic cortical neurogenesis.
Kara Goodkey+11 more
doaj +2 more sources
Development of the mammalian main olfactory bulb
The mammalian main olfactory bulb is a crucial processing centre for the sense of smell. The olfactory bulb forms early during development and is functional from birth.
Candida Tufo+5 more
semanticscholar +1 more source
The source of spontaneous activity in the main olfactory bulb of the rat. [PDF]
In vivo, most neurons in the main olfactory bulb exhibit robust spontaneous activity. This paper tests the hypothesis that spontaneous activity in olfactory receptor neurons drives much of the spontaneous activity in mitral and tufted cells via ...
Josif Stakic+3 more
doaj +1 more source