Results 161 to 170 of about 247,698 (320)

A comprehensive benchmarking for spatially resolved transcriptomics clustering methods across variable technologies, organs, and replicates

iMeta, EarlyView.
Spatial clustering is a critical step in spatially resolved transcriptomics. Here, we conducted a comprehensive benchmarking analysis of 14 spatial clustering methods using ~600 datasets, including both real‐world and simulated data spanning ten technologies and eight organs.
Renjie Chen, Yue Yao, Jingyang Qian, Xin Peng, Xin Shao, Xiaohui Fan   +5 more
wiley   +1 more source

SARS-CoV-2-Related Olfactory Dysfunction: Autopsy Findings, Histopathology, and Evaluation of Viral RNA and ACE2 Expression in Olfactory Bulbs

Biomedicines
Background: The COVID-19 pandemic has been a health emergency with a significant impact on the world due to its high infectiousness. The disease, primarily identified in the lower respiratory tract, develops with numerous clinical symptoms affecting ...
Marco Dell’Aquila, Concetta Cafiero, Alessandra Micera, Egidio Stigliano, Maria Pia Ottaiano, Giulio Benincasa, Beniamino Schiavone, Leo Guidobaldi, Luigi Santacroce, Salvatore Pisconti, Vincenzo Arena, Raffaele Palmirotta   +11 more
doaj   +1 more source

Detection of β-N-methylamino-l-alanine in postmortem olfactory bulbs of Alzheimer’s disease patients using UHPLC-MS/MS: An autopsy case-series study

, 2023
Susanna P. Garamszegi, Sandra Anne Banack, Linda Duque, James S. Metcalf, Elijah W. Stommel, Paul Alan Cox, David A. Davis   +6 more
openalex   +1 more source

Assessment of Small Vessel Density Changes in Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalophy (CADASIL) by High‐Resolution Black‐Blood MRI

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background Direct assessments of cerebral small vessels in Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy (CADASIL) remain a challenge. Purpose To investigate changes of cerebral small vessels in CADASIL using iso‐0.5 mm black‐blood MRI. Study Type Case control study.
Zidong Yang, Fanhua Guo, Steve Mendoza, Ziyang Huang, Yingying Li, Yunqing Ying, Xin Cheng, Qi Yang, Yonggang Shi, Danny J. J. Wang   +9 more
wiley   +1 more source

Intranasal Instillation of Aflatoxin B1 in Rats: Bioactivation in the Nasal Mucosa and Neuronal Transport to the Olfactory Bulb [PDF]

, 2000
Peter Larsson
openalex   +1 more source

The Sense of Smell (SoS) Atlas: Its Creation and First Application to Investigate COVID‐19 Related Anosmia With a Comprehensive Quantitative MRI Protocol

Journal of Magnetic Resonance Imaging, EarlyView.
ABSTRACT Background The loss of smell (anosmia) has been noted in numerous diseases, including COVID‐19. Inflammatory and microstructural alterations are possible underlying mechanisms of anosmia in COVID‐19. However, no atlas exists to study olfaction and the associated tissue property changes.
Marta Gaviraghi, Eleonora Lupi, Elena Grosso, Andrea Fusari, Mattia Baiguera, Anita Monteverdi, Marco Battiston, Francesco Grussu, Baris Kanber, Ferran Prados Carrasco, Rebecca S. Samson, Janine Makaronidis, Marios C. Yiannakas, Michael S. Zandi, Rachel L. Batterham, Egidio D'Angelo, Fulvia Palesi, Claudia A. M. Gandini Wheeler‐Kingshott   +17 more
wiley   +1 more source

Olfactory Bulb

Definitions, 2020

semanticscholar   +1 more source

Optimizing Odorants for Olfactory Training Based on Olfactory Receptor–Ligand Pair Analysis

The Laryngoscope, EarlyView.
This study employs receptor–ligand interaction analysis and olfactory epithelium transcriptomics to optimize olfactory training (OT). A novel four‐odorant combination (galaxolide, eugenol acetate, [−]‐menthol, geranyl acetate) activates 83.9% of 385 human olfactory receptors (ORs), covering 69.9% of estimated OR expression—significantly outperforming ...
Hironobu Nishijima, Eric H. Holbrook, James E. Schwob, Eri Mori, Ryoji Kagoya, Kei Ogawa, Kyohei Horikiri, Kenji Kondo   +7 more
wiley   +1 more source

Mechanisms and benefits of granule cell latency coding in the mouse olfactory bulb [PDF]

, 2012
Sonya Giridhar, Nathaniel N. Urban
openalex   +1 more source

Nasal Branch of the Anterior Ethmoidal Artery and Cribroethmoidal Groove: New Frontal Sinus Landmarks

The Laryngoscope, EarlyView.
This study investigates the nasal branch of the anterior ethmoidal artery (NbAEA) and the cribroethmoidal groove (CrEGr) as novel and reliable anatomical landmarks for expanded endoscopic frontal sinusotomies. Through cadaveric dissections and a clinical case series, both structures were consistently identified and shown to aid safe and accurate ...
Alessandro Vinciguerra, Mario Turri‐Zanoni, Pierfrancesco Bettini, Alberto Daniele Arosio, Alberto Gandolfi, Daniel Balzi, Gloria Schiavo, Federico Russo, Marco Valentini, Marco Ferrari, Paolo Castelnuovo, Philippe Herman, Maurizio Bignami, Paolo Battaglia   +13 more
wiley   +1 more source