Neural connectivity predicts spreading of alpha-synuclein pathology in fibril-injected mouse models: Involvement of retrograde and anterograde axonal propagation. [PDF]
, 2020 In Parkinson's disease, some of the first alpha-synuclein aggregates appear in the olfactory system and the dorsal motor nucleus of the vagus nerve before spreading to connected brain regions.
Brundin, Patrik +3 more
core +2 more sources
Epilepsia Open, EarlyView., 2022 Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica +6 more
wiley +1 more source
Drug-induced Parkinson's disease modulates protein kinase A and Olfactory Marker Protein in the mouse olfactory bulb [PDF]
, 2017 Background Olfaction is often affected in parkinsonian patients, but dopaminergic cells in the olfactory bulb are not affected by some Parkinson-inducing drugs.
Caretta, Antonio, Mucignat, Carla
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Synaptophysin and synaptoporin expression in the developing rat olfactory system [PDF]
, 1993 The expressions of two closely related synaptic vesicle antigens synaptophysin and synaptoporin were examined in the olfactory system of the adult rat and during pre- and postnatal development.
Bayer +50 more
core +1 more source
Lack of Pattern Separation in Sensory Inputs to the Olfactory Bulb during Perceptual Learning. [PDF]
, 2017 Recent studies revealed changes in odor representations in the olfactory bulb during active olfactory learning (Chu et al., 2016; Yamada et al., 2017).
Chu, Monica W +2 more
core +3 more sources
Olfactory Sensory Axons Expressing a Dominant–Negative Semaphorin Receptor Enter the CNS Early and Overshoot Their Target [PDF]
, 2000 Sensory axons extend from the chick olfactory epithelium to the telencephalon well before the maturation of their target, the olfactory bulb. During a waiting period of several days, olfactory axons arrive and accumulate outside the CNS while the bulb ...
Renzi, Michael J +2 more
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Chromogranin A in the olfactory system of the rat [PDF]
, 1990 The olfactory bulb of the rat contains chromogranin A at a similar level as the adrenal gland or the hypophysis as revealed by immunoblots. Olfactory chromogranin A also displays the same size as chromogranin A of endocrine cells.
Baker +32 more
core +1 more source
Evidence that pioneer olfactory axons regulate telencephalon cell cycle kinetics to induce the formation of the olfactory bulb [PDF]
, 1995 Early olfactory axons follow a specific pathway to reach the developing telencephalon. We observed that a subpopulation of these axons, the pioneer olfactory axons, penetrate into the ventricular zone of a highly restricted region of the telencephalon at
Gong, Qizhi, Shipley, Michael T
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Volumetric study of the olfactory bulb in patients with chronic rhinonasal sinusitis using MRI [PDF]
, 2016 ObjectiveOlfaction plays an important role in human daily life. The olfactory bulb size is dependent on stimulation. Smell loss is one of the main symptoms in chronic rhinonasal sinusitis. MRI has been indicated to evaluate the size of the olfactory bulb
Alarabawy, Reda A. +2 more
core +2 more sources
Massive normalization of olfactory bulb output in mice with a 'monoclonal nose' [PDF]
, 2016 Perturbations in neural circuits can provide mechanistic understanding of the neural correlates of behavior. In M71 transgenic mice with a 'monoclonal nose', glomerular input patterns in the olfactory bulb are massively perturbed and olfactory behaviors ...
Diodato, A +8 more
core +1 more source