Effect of low frequency stimulation of olfactory bulb and olfactory epithelium on epileptiform activity and synaptic plasticity following pentylenetetrazol administration in rats. [PDF]
Choupankareh S +7 more
europepmc +1 more source
ABSTRACT Over the past three decades, the global burden of common metabolic diseases such as obesity, diabetes, and atherosclerosis has steadily increased, becoming a serious public health issue that poses a major threat to human health worldwide. Potassium channels, particularly the voltage‐gated Kv1.3 subtype, serve as critical regulators of cellular
Wenjun Zhen +6 more
wiley +1 more source
Olfactory bulb differently synchronizes ventral hippocampus-medial prefrontal cortex circuit during spatial working memory across social dominance hierarchies. [PDF]
Bakhshi Jifroudi E +5 more
europepmc +1 more source
Metabolic Reprogramming and Exosome Remodeling in an Ndufs4‐Deficient Model of Leigh Syndrome
Ndufs4 knockout drives exosomal remodeling, reprograms cellular metabolism, impairs neural stem cell self‐renewal and differentiation, and suppresses mTOR signaling, providing a conceptual framework for understanding Leigh syndrome pathogenesis and informing therapeutic development.
Yakun Liu +13 more
wiley +1 more source
Microplastics as a Silent Threat to Child Neurodevelopment: Evidence and Perspectives on Autism
Microplastics and nanoplastics can likely cross various biological barriers and promote the development of oxidative stress and neuroinflammation, and they can also interfere with crucial events during brain development. Although none of these effects are causally linked to autism spectrum disorders, the microparticles and nanoparticles are the first ...
David Santos Grillo +5 more
wiley +1 more source
Prenatal alcohol exposure perturbs the development of radial glial cells in the fetal olfactory bulb. [PDF]
Kawasawa YI +3 more
europepmc +1 more source
Schematic illustration on a therapeutic strategy wherein engineered extracellular vesicles (EVs) are delivered intranasally and specifically target pericytes. In a model of chronic cerebral hypoperfusion (BCAS), this targeted approach preserves cerebral blood flow, reinforces blood‐brain barrier (BBB) integrity, stabilizes the neurovascular unit (NVU),
Weiwei Shen +11 more
wiley +1 more source
Decision revisions modulated by synaptic inhibition in the olfactory bulb facilitate learning
Pandey S +5 more
europepmc +1 more source
Intranasal Delivery of Bacterial Extracellular Vesicles Enables RNA Cargo Entry Into the Brain
ABSTRACT Extracellular vesicles (EVs) released by bacteria are potent mediators of host–microbe interactions. They modulate immune responses, deliver functional molecules and influence disease progression. However, whether bacterial EVs can access the brain and functionally affect host cells remains unclear.
Jae Yeong Ha +8 more
wiley +1 more source
Interleukin-1β depresses neuronal activity in the rat olfactory bulb even during odor stimulation. [PDF]
Jiménez A +8 more
europepmc +1 more source

