Results 231 to 240 of about 52,860 (309)

The Role of Magnetic Resonance Spectroscopy (MRS), Diffusion‐Tensor‐Imaging (DTI) and Structural MRI in the Alzheimer's Disease and Mild Cognitive Impairment Diagnosis: A Review

open access: yesJournal of Magnetic Resonance Imaging, Volume 63, Issue 6, Page 1509-1545, June 2026.
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca   +3 more
wiley   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

open access: yesMedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu   +9 more
wiley   +1 more source

The Use of Statins in Parkinson's and Alzheimer's Disease: A 2021–2025 State‐of‐the‐Art Review of Clinical and Preclinical Evidence

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto   +7 more
wiley   +1 more source

Psychosocial Factors Mediate the Relationship Between Olfactory Function and Cognitive Frailty in Older Adults: A Structural Equation Modelling

open access: yesAustralasian Journal on Ageing, Volume 45, Issue 2, June 2026.
ABSTRACT Objective With the trend of population ageing, cognitive frailty in older adults is an increasingly pressing public health issue. Identifying early‐stage risk factors has become a key priority for researchers with the goal of preventing disability.
Li‐Jun Chen   +6 more
wiley   +1 more source

Convergent reduction of olfactory genes and olfactory bulb size in mammalian species at altitude. [PDF]

open access: yesCurr Biol
Graham AM   +7 more
europepmc   +1 more source

Expanding the Phenotypic Spectrum Associated With Loss‐of‐Function SMARCA4 Variants to Eye Developmental Anomalies

open access: yesClinical Genetics, Volume 109, Issue 6, Page 1064-1069, June 2026.
This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau   +7 more
wiley   +1 more source

Olfactory bulb interneurons - The developmental timeline and targeting defined by embryonic neurogenesis. [PDF]

open access: yesMol Cell Neurosci
Spence NJ   +6 more
europepmc   +1 more source

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