Results 231 to 240 of about 52,860 (309)
ABSTRACT Alzheimer's disease (AD) is one of the most common neurological disorders affecting older adults, with approximately 7.2 million cases only in the United States. This number is projected to increase to 13.8 million in the United States by 2060, leading to increased expenditures for healthcare, long‐term care and hospice services. Consequently,
Valentina Zecca +3 more
wiley +1 more source
Connexin 36-mediated gap junctions contribute to fine odour discrimination and late-phase excitation of mitral cells in the mouse olfactory bulb. [PDF]
Kuruppath P +5 more
europepmc +1 more source
Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu +9 more
wiley +1 more source
Odor encoding by fine-timescale spike synchronization patterns in the olfactory bulb. [PDF]
Werth JC, Einhorn M, Cleland TA.
europepmc +1 more source
ABSTRACT Statins, widely prescribed for cardiovascular prevention, have emerged as potential disease‐modifying agents in neurodegenerative disorders due to their pleiotropic effects on cholesterol metabolism, neuroinflammation, oxidative stress, and protein aggregation.
Luigi Maria Chiatto +7 more
wiley +1 more source
Ultrastructural Contributions to Extrasynaptic Glutamatergic Signaling in Olfactory Bulb Glomeruli. [PDF]
Bourne JN, Schoppa NE.
europepmc +1 more source
ABSTRACT Objective With the trend of population ageing, cognitive frailty in older adults is an increasingly pressing public health issue. Identifying early‐stage risk factors has become a key priority for researchers with the goal of preventing disability.
Li‐Jun Chen +6 more
wiley +1 more source
Convergent reduction of olfactory genes and olfactory bulb size in mammalian species at altitude. [PDF]
Graham AM +7 more
europepmc +1 more source
This study expands the clinical spectrum of SMARCA4 by describing a novel phenotype in three unrelated individuals with truncating variants. Distinct from Coffin–Siris syndrome and rhabdoid tumor predisposition, this new association is characterized by ocular malformations, specifically microphthalmia and coloboma.
Bertrand Chesneau +7 more
wiley +1 more source
Olfactory bulb interneurons - The developmental timeline and targeting defined by embryonic neurogenesis. [PDF]
Spence NJ +6 more
europepmc +1 more source

