Results 231 to 240 of about 250,076 (386)

Evidence of COMT dysfunction in the olfactory bulb in Parkinson's disease. [PDF]

open access: yesActa Neuropathol
Beauchamp LC   +12 more
europepmc   +1 more source

Effect of prolonged voluntary wheel running on oxidative stress and defence mechanisms in cortex and hippocampus of healthy female rats

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 449-463, 1 February 2026.
Abstract Physical exercise promotes brain health and cognitive function possibly through mechanisms that include strengthened resistance to oxidative stress. However, limited research has explored the cumulative effects of regular voluntary exercise on both oxidative stress and defence mechanisms in hippocampus and cortex, two regions essential for ...
Camilla Myrup Holst   +6 more
wiley   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou   +5 more
wiley   +1 more source

Orexin Receptor Antagonism Improves Sleep Quality and Mitigates Lipopolysaccharide‐Induced Inflammatory Responses in a Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Inhibiting orexin improves sleep quality and mitigates inflammation of LPS‐induced mice. ABSTRACT Alterations in the immune system, stemming from sleep/wakefulness disorders, increase the risk of inflammatory pathologies. Orexin, a hypothalamic neuropeptide, regulates sleep and wakefulness.
Dai Horiuchi   +7 more
wiley   +1 more source

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