Results 251 to 260 of about 243,434 (387)

Acidic Nanoparticles Prevent HIV Pre‐Exposure Prophylaxis (PrEP)‐Induced Oligodendrocyte Impairments by Restoring Lysosomal pH in Adolescent Models

open access: yesGlia, Volume 73, Issue 10, Page 1967-1988, October 2025.
Main Points Pre‐exposure prophylaxis (PrEP) inhibits oligodendrocyte differentiation PrEP inhibits oligodendrocyte differentiation through lysosome deacidification Acidic nanoparticles prevent PrEP‐induced inhibition of oligodendrocyte differentiation ABSTRACT A disproportionate percentage of adolescents are diagnosed with human immunodeficiency virus (
Caela C. Long   +6 more
wiley   +1 more source

Glial cells in the mammalian olfactory bulb. [PDF]

open access: yesFront Cell Neurosci
Zhao D, Hu M, Liu S.
europepmc   +1 more source

Importance of newly generated neurons in the adult olfactory bulb for odor discrimination [PDF]

open access: green, 2000
Gilles Gheusi   +5 more
openalex   +1 more source

Shared Lineage, Distinct Outcomes: Yap and Taz Loss Differentially Impact Schwann and Olfactory Ensheathing Cell Development Without Disrupting GnRH‐1 Migration

open access: yesGlia, Volume 73, Issue 10, Page 2077-2097, October 2025.
Main Points OECs, SCs, and Mel derive from SCPs. Sox10Cre;YapHet;TazKO mice show impaired SC maturation, reduced Mel formation, fewer SCPs, OECs, and olfactory neurons, but normal GnRH‐1 neuron migration. ABSTRACT Olfactory Ensheathing Cells (OECs) are glial cells originating from the neural crest and are critical for bundling olfactory axons to the ...
Ed Zandro M. Taroc   +7 more
wiley   +1 more source

Ex Vivo Functional Characterization of Mouse Olfactory Bulb Projection Neurons Reveals a Heterogeneous Continuum. [PDF]

open access: yeseNeuro
Gadiwalla S   +6 more
europepmc   +1 more source

Myelin Lipid Composition in the Central Nervous System Is Regionally Distinct and Requires Mechanistic Target of Rapamycin Signaling

open access: yesGlia, Volume 73, Issue 9, Page 1841-1859, September 2025.
Main Points Brain oligodendrocytes have lower rates of cholesterol synthesis and higher rates of lipoprotein uptake than spinal cord oligodendrocytes. Myelin lipid content is higher in CNS regions with larger average axon diameter. Brain and spinal cord myelin cholesterol content is innately different, while myelin fatty acid content can be modulated ...
Marie L. Mather   +4 more
wiley   +1 more source

Zic3 enables bimodal regulation of tyrosine hydroxylase expression in olfactory bulb and midbrain-derived neurons. [PDF]

open access: yesCell Death Discov
Bhaskar S   +11 more
europepmc   +1 more source

Zebrafish as a Versatile Model Organism: From Tanks to Treatment

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
The zebrafish, with its optical transparency and genetic tractability, serves as a versatile in vivo platform for biomedical research. This review underscores its significance in modeling a wide spectrum of human diseases—from cancer to metabolic disorders—and in leveraging cutting‐edge technologies like CRISPR and TALENs.
Rupali Srivastava   +9 more
wiley   +1 more source

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