Results 61 to 70 of about 250,076 (386)
Nature Communications, 2017 Humans and other animals can recognize an odorant as the same over a range of odorant concentrations. It remains unclear whether the olfactory bulb, the brain structure that mediates the first stage of olfactory information processing, participates in ...
Douglas A. Storace, L. Cohen
semanticscholar +1 more source
A subtype-specific critical period for neurogenesis in the postnatal development of mouse olfactory glomeruli. [PDF]
PLoS ONE, 2012 Sensory input is essential for the normal development of sensory centers in the brain, such as the somatosensory, visual, auditory, and olfactory systems.
Yasuko Kato +6 more
doaj +1 more source
Metastasizing esthesioneuroblastoma in a dog [PDF]
, 2014 A 7-year-old Afghan hound presented with a history of disorientation, loss of vision, and seizures. Magnetic resonance imaging helped identify a mass at the level of the main olfactory bulb that compressed and displaced adjacent tissues in the cribriform
Herden, Christiane +3 more
core +1 more source
A ventral glomerular deficit in Parkinson’s disease revealed by whole olfactory bulb reconstruction
Brain : a journal of neurology, 2017 Olfactory dysfunction is common in Parkinson’s disease. Zapiec et al. devise a rigorous quantitative approach to describe the glomerular component of the entire human olfactory bulb.
Bolek Zapiec +5 more
semanticscholar +1 more source
Nature Communications, 2017 Cholinergic neurons in the basal forebrain project heavily to the main olfactory bulb, the first processing station in the olfactory pathway. The projections innervate multiple layers of the main olfactory bulb and strongly influence odor discrimination,
Daniel T. Case +5 more
semanticscholar +1 more source
Neural Regeneration Research, 2018 Hyperhomocysteinemia has been shown to be associated with neurodegenerative diseases; however, lesions or histological changes and mechanisms underlying homocysteine-induced injury in olfactory bulb neurons remain unclear.
Jing-wen Zhang +6 more
doaj +1 more source
Metal concentrations and distributions in the human olfactory bulb in Parkinson’s disease
Scientific Reports, 2017 In Parkinson’s disease (PD), the olfactory bulb is typically the first region in the body to accumulate alpha-synuclein aggregates. This pathology is linked to decreased olfactory ability, which becomes apparent before any motor symptoms occur, and may ...
Bronwen Gardner +6 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
The Origin, Development and Molecular Diversity of Rodent Olfactory Bulb Glutamatergic Neurons Distinguished by Expression of Transcription Factor NeuroD1. [PDF]
PLoS ONE, 2015 Production of olfactory bulb neurons occurs continuously in the rodent brain. Little is known, however, about cellular diversity in the glutamatergic neuron subpopulation.
Laurent Roybon +7 more
doaj +1 more source
Odor-Induced Neuronal Rhythms in the Olfactory Bulb Are Profoundly Modified in ob/ob Obese Mice [PDF]
, 2017 Leptin, the product of the Ob(Lep) gene, is a peptide hormone that plays a major role in maintaining the balance between food intake and energy expenditure. In the brain, leptin receptors are expressed by hypothalamic cells but also in the olfactory bulb,
Amandine Everard +6 more
core +3 more sources