Results 61 to 70 of about 83,412 (292)

Novel subdomains of the mouse olfactory bulb defined by molecular heterogeneity in the nascent external plexiform and glomerular layers [PDF]

open access: yes, 2007
Background: In the mouse olfactory system, the role of the olfactory bulb in guiding olfactory sensory neuron (OSN) axons to their targets is poorly understood. What cell types within the bulb are necessary for targeting is unknown.
Williams, Eric O   +6 more
core   +2 more sources

Anatomic Diagram as a Novel Assessment Strategy for Subclinical Local Residual Disease in Sinonasal Squamous Cell Carcinoma and Intestinal‐type Adenocarcinoma

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Objective In the last two decades, transnasal endoscopic surgery (TES) has become pivotal in the management of sinonasal tumors. This approach involves a multiblock tumor resection, adding complexity to the interpretation of surgical margins after pathological examination.
Piergiorgio Gaudioso   +14 more
wiley   +1 more source

Tryptophan-5-HT pathway disorder was uncovered in the olfactory bulb of a depression mice model by metabolomic analysis

open access: yesFrontiers in Molecular Neuroscience, 2022
Major depression (MD) is a severe mental illness that creates a heavy social burden, and the potential molecular mechanisms remain largely unknown. Lots of research demonstrate that the olfactory bulb is associated with MD.
Guanghui Chen   +6 more
doaj   +1 more source

Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population‐Based Rhineland Study

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng   +4 more
wiley   +1 more source

Immature olfactory sensory neurons provide behaviourally relevant sensory input to the olfactory bulb

open access: yesNature Communications, 2022
New olfactory sensory neurons (OSNs) wire into highly organized olfactory bulb circuits throughout life. Here, the authors show that immature OSNs provide behaviourally relevant sensory input to olfactory bulb neurons that is functionally distinct from ...
Jane S. Huang   +9 more
doaj   +1 more source

Olfactory Neuroscience: Beyond the Bulb [PDF]

open access: yesCurrent Biology, 2011
High-resolution tracing of projections from the olfactory bulb to its cortical targets revealed coarse topography and stereotopy in some areas but highly distributed, combinatorial connectivity in others. These results provide a basis for understanding innate and associative olfactory processing and perception.
openaire   +2 more sources

Development of P2 olfactory glomeruli in P2-internal ribosome entry site-tau-lacZ transgenic mice [PDF]

open access: yes, 1999
Primary olfactory neurons project their axons to the olfactory bulb, where they terminate in discrete loci called glomeruli. All neurons expressing the same odorant receptor appear to terminate in a few glomeruli in each olfactory bulb.
Key, Brian, Royal, Stephanie J.
core   +2 more sources

Scalp electroacupuncture targeting trigeminal nerve activation alleviates post‐traumatic stress disorder–induced depression and neuroinflammation in mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Scalp electroacupuncture (SA) through activation of the trigeminal pathway exerts anti‐inflammatory, antidepressant, and anxiolytic effects in an animal model of post‐traumatic stress disorder induced by single prolonged stress. This suggests that SA is involved in neuroinflammation and changes in brain‐derived neurotrophic factor protein through the ...
Bombi Lee   +3 more
wiley   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng   +9 more
wiley   +1 more source

Paced-mating increases the number of adult new born cells in the internal cellular (granular) layer of the accessory olfactory bulb. [PDF]

open access: yesPLoS ONE, 2011
The continuous production and addition of new neurons during life in the olfactory bulb is well accepted and has been extensively studied in rodents. This process could allow the animals to adapt to a changing environment.
Rebeca Corona   +2 more
doaj   +1 more source

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