Results 61 to 70 of about 243,434 (387)
Nature Communications, 2017 Humans and other animals can recognize an odorant as the same over a range of odorant concentrations. It remains unclear whether the olfactory bulb, the brain structure that mediates the first stage of olfactory information processing, participates in ...
Douglas A. Storace, L. Cohen
semanticscholar +1 more source
Olfactory Neuroscience: Beyond the Bulb [PDF]
Current Biology, 2011 High-resolution tracing of projections from the olfactory bulb to its cortical targets revealed coarse topography and stereotopy in some areas but highly distributed, combinatorial connectivity in others. These results provide a basis for understanding innate and associative olfactory processing and perception.
openaire +3 more sources
Neural Regeneration Research, 2018 Hyperhomocysteinemia has been shown to be associated with neurodegenerative diseases; however, lesions or histological changes and mechanisms underlying homocysteine-induced injury in olfactory bulb neurons remain unclear.
Jing-wen Zhang +6 more
doaj +1 more source
A ventral glomerular deficit in Parkinson’s disease revealed by whole olfactory bulb reconstruction
Brain : a journal of neurology, 2017 Olfactory dysfunction is common in Parkinson’s disease. Zapiec et al. devise a rigorous quantitative approach to describe the glomerular component of the entire human olfactory bulb.
Bolek Zapiec +5 more
semanticscholar +1 more source
Rewiring Neuroimmunity: Nanoplatform Innovations for CNS Disease Therapy
Advanced Therapeutics, EarlyView.This review explores emerging nanoplatform strategies designed to modulate neuroimmune responses for treating central nervous system (CNS) disorders. It examines structural and microenvironmental barriers, advances in multifunctional and targeted nanotechnologies, and highlights clinical progress and translational challenges, offering insights into the
Muhammad Usman Akbar +7 more
wiley +1 more source
Frontiers in Neuroanatomy, 2014 The olfactory bulb is an evolutionarily old structure that antedates the appearance of a six-layered mammalian cerebral cortex. As such, the neuronal scaling rules that apply to scaling the mass of the olfactory bulb as a function of its number of ...
Pedro Furtado De Mattos Ribeiro +4 more
doaj +1 more source
Consolidation of an olfactory memory trace in the olfactory bulb is required for learning-induced survival of adult-born neurons and long-term memory. [PDF]
PLoS ONE, 2010 BACKGROUND: It has recently been proposed that adult-born neurons in the olfactory bulb, whose survival is modulated by learning, support long-term olfactory memory.
Florence Kermen +4 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song +24 more
wiley +1 more source
Open housing drives the expression of immune response genes in the nasal mucosa, but not the olfactory bulb. [PDF]
PLoS ONE, 2017 Nasal mucosa and olfactory bulb are separated by the cribriform plate which is perforated by olfactory nerves. We have previously demonstrated that the cribriform plate is permissive for T cells and monocytes and that viruses can enter the bulb upon ...
Carolin Piotrowski +7 more
doaj +1 more source
Nature Communications, 2017 Cholinergic neurons in the basal forebrain project heavily to the main olfactory bulb, the first processing station in the olfactory pathway. The projections innervate multiple layers of the main olfactory bulb and strongly influence odor discrimination,
Daniel T. Case +5 more
semanticscholar +1 more source