Results 131 to 140 of about 670,781 (328)

Insulin Modulates Neural Activity of Pyramidal Neurons in the Anterior Piriform Cortex

open access: yesFrontiers in Cellular Neuroscience, 2017
Insulin is an important peptide hormone that regulates food intake and olfactory function. While a multitude of studies investigated the effect of insulin in the olfactory bulb and olfactory epithelium, research on how it modulates higher olfactory ...
Yang Zhou   +6 more
doaj   +1 more source

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu   +9 more
wiley   +1 more source

Stem Cell Niches for Olfactory Regeneration and Their Therapeutic Applications [PDF]

open access: yesJournal of Rhinology
Olfactory dysfunction affects many individuals and may result from infections, trauma, neurodegenerative diseases, or genetic disorders. Unlike most neurons in the mammalian nervous system, olfactory sensory neurons (OSNs) continuously regenerate ...
Yun Jin Kang, David W. Jang, Do Hyun Kim
doaj   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, EarlyView.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

Devices, Functions, and Applications of Artificial Neuromorphic Visual Systems

open access: yesAdvanced Science, EarlyView.
This review highlights recent advances in optoelectronic synapses for artificial neuromorphic vision, emphasizing their material systems, structural designs, and performance metrics. It further discusses visual neural networks enabled by these synapses, covering perception, memory, and recognition functionalities, and analyzes challenges in stability ...
Jiaxin Liu   +4 more
wiley   +1 more source

fMRI Evidence for Modality-Specific Processing of Conceptual Knowledge on Six Modalities [PDF]

open access: yes, 2003
Traditional theories assume that amodal representations, such as feature lists and semantic networks, represent conceptual knowledge about the world. According to this view, the sensory, motor, and introspective states that arise during perception and ...
Barsalou, L.W.   +4 more
core  

Chemosensory Convergence on Primary Olfactory Cortex

open access: yesJournal of Neuroscience, 2012
Food perception and preference formation relies on the ability to combine information from both the taste and olfactory systems. Accordingly, psychophysical investigations in humans and behavioral work in animals has shown that the taste system plays an ...
Joost X. Maier, M. Wachowiak, D. Katz
semanticscholar   +1 more source

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