Elevated tau in the piriform cortex in Alzheimer's but not Parkinson's disease using PET‐MR [PDF]
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease MonitoringINTRODUCTION Olfactory dysfunction can be an early sign of Alzheimer's disease (AD). We used tau positron emission tomography‐magnetic resonance (PET‐MR) to analyze a key region of the olfactory circuit, the piriform cortex, in comparison to the adjacent
Hossein Moein Taghavi +18 more
doaj +3 more sources
The Role of the Piriform Cortex in Temporal Lobe Epilepsy: A Current Literature Review [PDF]
Frontiers in Neurology, 2022 Temporal lobe epilepsy is the most common form of focal epilepsy and can have various detrimental consequences within many neurologic domains. Recent evidence suggests that the piriform cortex may also be implicated in seizure physiology.
Daniel R Kramer
exaly +4 more sources
Volumetric Analysis of the Piriform Cortex in Temporal Lobe Epilepsy [PDF]
Epilepsy Research, 2022 The piriform cortex, at the confluence of the temporal and frontal lobes, generates seizures in response to chemical convulsants and electrical stimulation.
Alexander Hammers +2 more
exaly +5 more sources
Dynamic recovery of piriform cortex function and its impact on cognitive processing speed following mild COVID-19 [PDF]
BMC NeurologyBackground Although the neurological sequelae of severe COVID-19 are increasingly recognized, the long-term neural impact of uncomplicated mild SARS-CoV-2 infection remains insufficiently characterized.
Hyeonseok Jeong +8 more
doaj +2 more sources
Interictal blood–brain barrier dysfunction in piriform cortex of people with epilepsy [PDF]
Annals of Clinical and Translational NeurologyObjective The piriform cortex is considered to be highly epileptogenic. Its resection during epilepsy surgery is a predictor for postoperative seizure freedom in temporal lobe epilepsy. Epilepsy is associated with a dysfunction of the blood–brain barrier.
Freya Schulte +20 more
doaj +2 more sources
LRP4 is required for the olfactory association task in the piriform cortex [PDF]
Cell & Bioscience, 2022 Background Low-density lipoprotein receptor-related protein 4 (LRP4) plays a critical role in the central nervous system (CNS), including hippocampal synaptic plasticity, maintenance of excitatory synaptic transmission, fear regulation, as well as long ...
Min Yan +12 more
doaj +2 more sources
PLoS ONE, 2011 The piriform cortex receives input from the olfactory bulb and (via the entorhinal cortex) sends efferents to the hippocampus, thereby connecting the two canonical neurogenic regions of the adult rodent brain.
Helmut Kettenmann +2 more
exaly +3 more sources
Doublecortin-immunoreactive neurons in the piriform cortex are sensitive to the long lasting effects of early life stress [PDF]
Frontiers in NeuroscienceThe olfactory system is a niche of continuous structural plasticity, holding postnatal proliferative neurogenesis in the olfactory bulbs and a population of immature neurons in the piriform cortex.
María Abellán-Álvaro +8 more
doaj +2 more sources
Essential Role of the Anterior Piriform Cortex in Mediating Social Novelty Output via a Top–Down Circuit [PDF]
Advanced ScienceSocial novelty is indispensable for a wide range of social behaviors. The medial prefrontal cortex (mPFC), along with other social information hubs, composes the foundational circuitry of social novelty.
Jingwei Zhou +10 more
doaj +2 more sources
Differential connectivity of the posterior piriform cortex in Parkinson’s disease and postviral olfactory dysfunction: an fMRI study [PDF]
Scientific ReportsOlfactory dysfunction is a common feature of both postviral upper respiratory tract infections (PV) and idiopathic Parkinson’s disease (PD). Our aim was to investigate potential differences in the connectivity of the posterior piriform cortex, a major ...
Charalampos Georgiopoulos +5 more
doaj +2 more sources