Results 201 to 210 of about 477,767 (296)
Purpose The dependence of the long‐time (tortuosity) limit of the extra‐cellular diffusivity on the intra‐cellular volume fraction is of fundamental importance for microstructure modeling. While such dependencies have been explored for the white matter, the tortuosity limit in gray matter is unknown due to complex cell composition and geometry. Here we
Hong‐Hsi Lee +6 more
wiley +1 more source
Altered functional connectivity of primary olfactory cortex-hippocampus-frontal cortex in subjective cognitive decline during odor stimulation. [PDF]
Zhang X +14 more
europepmc +1 more source
Clinical management of a severe skull fracture in a loggerhead sea turtle (Caretta caretta)
Abstract A 30.6 kg loggerhead sea turtle (Caretta caretta) presented with a 2–3‐week‐old deep head wound, left neck and right cubital lacerations, and carapace fractures. Haematology revealed a marked leukocytosis, with other values unremarkable. Initial wound‐cleaning, an antibiotic course, fluids and vitamin B supplementation were initiated. Computed
Madeline Yde +4 more
wiley +1 more source
GABAergic neurons in the olfactory cortex projecting to the lateral hypothalamus in mice. [PDF]
Murata K +11 more
europepmc +1 more source
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen +7 more
wiley +1 more source
Abstract Last year, we challenged the view that large‐bodied theropod dinosaurs such as Tyrannosaurus rex resembled primates in cognition and behavior, a proposition made by Herculano‐Houzel in 2023. More recently, Jensen et al. have criticized our work on this topic, raising methodological and conceptual issues.
Kai R. Caspar +5 more
wiley +1 more source
Metformin Attenuates Behavioral Deficits and Oxidative Stress in a Preclinical Model of Autism
ABSTRACT Autism spectrum disorder (ASD) is a complex neurodevelopmental condition lacking effective pharmacological treatments. Metformin has emerged as a candidate for drug repurposing in ASD due to its metabolic and neurobiological actions. This study evaluated the in vivo effects of metformin (400 mg/kg, orally) administered from postnatal day 21 to
Madna Costa Freitas +9 more
wiley +1 more source
Cell type–specific EVs were isolated from mouse brain and profiled by proteomics. Each EV subtype exhibited proteomic signatures consistent with the specialized functions of its cell of origin. Astrocyte‐derived EVs (ADEVs) were enriched for the GlialCAM/MLC1 network and GPCRs.
Alba M. Lucart‐Sanchez +7 more
wiley +1 more source
Microplastics and nanoplastics (MPs/NPs) are emerging environmental neurotoxicants capable of accumulating in the human brain through blood‐brain barrier transcytosis and olfactory transport pathways. Once within the central nervous system, MPs/NPs trigger interconnected mechanisms including NLRP3 inflammasome activation, oxidative stress ...
Alfi Sophian, Asmariani, Erika Ismayani
wiley +1 more source

