Results 271 to 280 of about 116,665 (335)

Does It Matter What Keeps You Awake? Effects of Two Different Sleep Deprivation Methods on Object‐Location Memory and Hippocampal c‐Fos Expression in Mice

open access: yesJournal of Sleep Research, Volume 35, Issue 1, February 2026.
ABSTRACT In sleep research, various sleep deprivation methods have been used to examine the effects of sleep loss on memory. However, studies often overlook the distinct impacts each method may have on activity in specific neuronal circuits and memory storage.
Adithya Sarma   +4 more
wiley   +1 more source

Effect of prolonged voluntary wheel running on oxidative stress and defence mechanisms in cortex and hippocampus of healthy female rats

open access: yesExperimental Physiology, Volume 111, Issue 2, Page 449-463, 1 February 2026.
Abstract Physical exercise promotes brain health and cognitive function possibly through mechanisms that include strengthened resistance to oxidative stress. However, limited research has explored the cumulative effects of regular voluntary exercise on both oxidative stress and defence mechanisms in hippocampus and cortex, two regions essential for ...
Camilla Myrup Holst   +6 more
wiley   +1 more source

Olfactory bulbectomy induces neurobiological alterations in the prefrontal cortex and hyperlocomotion in male rats. [PDF]

open access: yesPLoS One
Bautista-Carro MA   +6 more
europepmc   +1 more source

Metabolome Atlas of Brain Reveals Regional Shared and Unique Metabolic Drifts in Response to Type 2 Diabetes in Male Mice

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
A detailed metabolome atlas of the male mouse brain was established, incorporating metabolomic and lipidomic profiling of seven anatomical regions. T2D induced marked metabolic alterations, which were mainly associated with lipotoxicity, defective energy metabolism, proinflammatory processes, and neurotoxicity.
Yang Zhou   +5 more
wiley   +1 more source

Biochemical and Physiological Effects of Galanin in Health and Disease

open access: yesThe FASEB Journal, Volume 40, Issue 2, 31 January 2026.
Galanin is a biologically active neuropeptide hormone that mediates its effects through three galanin receptors. Galanin signaling induces changes in glucose homeostasis amongst others and plays a dynamic role in the physiological health of many organ systems.
Patrick Mireles   +3 more
wiley   +1 more source

Orexin Receptor Antagonism Improves Sleep Quality and Mitigates Lipopolysaccharide‐Induced Inflammatory Responses in a Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 1, 15 January 2026.
Inhibiting orexin improves sleep quality and mitigates inflammation of LPS‐induced mice. ABSTRACT Alterations in the immune system, stemming from sleep/wakefulness disorders, increase the risk of inflammatory pathologies. Orexin, a hypothalamic neuropeptide, regulates sleep and wakefulness.
Dai Horiuchi   +7 more
wiley   +1 more source

Dilated cardiomyopathy-associated RNA-binding motif protein 20 regulates long pre-mRNAs in neurons. [PDF]

open access: yesElife
Di Bartolomei G   +5 more
europepmc   +1 more source

Purkinje Cell Loss in Essential Tremor: Collective Data From 215 Brains Over a 21‐Year Period

open access: yesAnnals of Clinical and Translational Neurology, Volume 13, Issue 1, Page 36-48, January 2026.
ABSTRACT Objective Essential tremor is a highly prevalent movement disorder. Pathological changes observed in essential tremor cerebella center around Purkinje cells and neighboring neuronal populations. Postmortem studies have variably, but not always, shown reduced Purkinje cell counts in essential tremor compared to controls.
Chloë A. Kerridge   +4 more
wiley   +1 more source

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