Results 271 to 280 of about 115,804 (336)

Anatomical Associations Between Focal Mitochondrial Metabolism and Patterns of Neurodegeneration in Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, Volume 99, Issue 3, Page 614-628, March 2026.
Objective Amyotrophic lateral sclerosis (ALS) has a very specific neuroimaging signature, but the molecular underpinnings of the strikingly selective anatomic involvement have not elucidated to date. Accordingly, a large neuroimaging study was conducted with 258 participants to evaluate associations between patterns of neurodegeneration and focal ...
Marlene Tahedl   +10 more
wiley   +1 more source

Mapping Human Corpus Callosum Connectivity With Diffusion Spectrum Imaging: A Deterministic Tractography Approach

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
Our study developed a callosal template incorporating macro‐anatomic and long‐range connectional information, providing detailed transcallosal tracts and the corresponding topography of callosal subregions at high resolution using DSI techniques. In addition, the QA‐based structural connectome observed in this study reflects the relationship between ...
Chao Zhang   +11 more
wiley   +1 more source

Glymphatic System Dysfunction in Central Nervous System Diseases

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
Glymphatic Dysfunction in Neurological Disorders: The glymphatic system is a brain‐wide clearance system that removes neurotoxic waste via AQP4‐mediated CSF‐ISF exchange. Dysfunction through AQP4 mislocalization, BBB injury, and inflammation annihilates clearance and causes acute (stroke, TBI) and chronic disease.
Anwar Zahran   +14 more
wiley   +1 more source

ShenQi DiHuang Decoction (SQDHD) Ameliorates Neuroinflammation and Neuropsychiatric Manifestations in Pristane Induced Lupus Mice via Blocking JAK1‐STAT3 Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
SQDHD exerts neuroprotective effects and alleviates behavioral deficits in PIL mice, likely by inhibiting the JAK1‐STAT3 pathway in activated CVECs. These findings underscore the therapeutic potential of SQDHD and establish it as a promising candidate for the treatment of NPSLE.
Jie Chen   +9 more
wiley   +1 more source

Fetal Pain Perception: Legislative Assertions and Developmental Neuroscience

open access: yesAnnals of the Child Neurology Society, Volume 4, Issue 1, Page 15-28, March 2026.
ABSTRACT Background Pain perception is a conscious experience, but neither pain nor consciousness is defined in the developing human fetus. Emergent consciousness may be regarded as a phenomenon that ultimately arises from an essential minimum of functional neuronal connectivity. Proposed U.S.
William D. Graf   +9 more
wiley   +1 more source

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