Results 161 to 170 of about 52,033 (255)

Correlating symptoms and skin α-synuclein seeding parameters in olfactory dysfunction and Lewy body dementia. [PDF]

open access: yesJ Neurol
McWilliam OH   +12 more
europepmc   +1 more source

Olfactory‐Related Quality of Life After Endoscopic Transsphenoidal Surgery

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 4, August 2026.
The QOD‐LQ, QOD‐VAS, and the “decreased sense of smell” item of the SNOT‐22, reflecting olfactory‐related quality of life (QOL) and subjective olfactory dysfunction, significantly deteriorated after EETSA in a substantial proportion of patients, even though psychophysical olfactory function was preserved.
Yeong Ju Lee   +4 more
wiley   +1 more source

Neuroimaging and Transcriptomic Insights Into Iron Accumulation and Glymphatic Dysfunction in Olfactory Dysfunction. [PDF]

open access: yesCNS Neurosci Ther
Leong C   +10 more
europepmc   +1 more source

Proteomic and Phosphoproteomic Characteristics of Multiple Brain Regions in Rhesus Macaques After SARS‐CoV‐2 Infection

open access: yesMedComm, Volume 7, Issue 8, August 2026.
The study found that SARS‐CoV‐2 Omicron infection causes region‐specific inflammatory, immune, synaptic, and signaling disorders in the brain, and the predicted kinases and differentially expressed proteins may serve as potential targets for COVID‐19‐related drug discovery.
Qiaochu Wang   +8 more
wiley   +1 more source

Dissociated Biologic Responses Across the United Airway: A Case Report of Severe Asthma With Chronic Rhinosinusitis With Nasal Polyps and Eosinophilic Otitis Media

open access: yesRespirology Case Reports, Volume 14, Issue 8, August 2026.
We report a case of severe asthma with chronic rhinosinusitis with nasal polyps and eosinophilic otitis media that was successfully controlled by switching biologic therapy from dupilumab to mepolizumab. Careful monitoring of disease activity and consideration of biologic switching may help achieve optimal control with currently available biologics ...
Tomoko Tajiri   +5 more
wiley   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

open access: yesVIEW, Volume 7, Issue 4, August 2026.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang   +5 more
wiley   +1 more source

HNRNPC Succinylation Influences the Neurodegeneration of Alzheimer's Disease Through YME1L1‐Mediated Mitochondrial Metabolism

open access: yesAging Cell, Volume 25, Issue 8, August 2026.
In Alzheimer's disease, SIRT5 downregulation enhances TRIM25‐mediated succinylation of HNRNPC at K50, increasing its stability. Stabilized HNRNPC upregulates YME1L1 expression via an m6A‐dependent mechanism, leading to OPA1 hydrolysis dysregulation, mitochondrial fission‐fusion imbalance, ROS overproduction, and neuronal death.
Xuewei Li   +4 more
wiley   +1 more source

A Cross-Sectional Study Exploring Patient Experiences, Unmet Needs and Desired Support in Those With Olfactory Dysfunction. [PDF]

open access: yesClin Otolaryngol
Ansley W   +13 more
europepmc   +1 more source

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