Results 151 to 160 of about 52,033 (255)

Brain‐Wide Mapping and Synaptic Localization of C1QL3 Using a Novel Epitope‐Tagged Knock‐In Mouse

open access: yesJournal of Comparative Neurology, Volume 534, Issue 8, August 2026.
C1QL3 is a secreted adhesion molecule that acts as a key regulator of synaptic structure and function. We generated and validated a novel epitope‐tagged knock‐in mouse line (C1ql32HA) in which two hemagglutinin (HA) epitopes were inserted near the N‐terminus of the endogenous C1QL3 protein.
William P. Armstrong IV   +12 more
wiley   +1 more source

Long COVID-19 olfactory dysfunction: discrepancy between psychophysical tests and self-perception. [PDF]

open access: yesBraz J Otorhinolaryngol
Sansa A   +6 more
europepmc   +1 more source

hUC‐MSCs via β‐NGF Alleviate Cognitive Impairment After Tibial Fracture Surgery by Regulating the STMN2/NMNAT2‐SARM1‐NF‐κB Signaling Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This study found that human umbilical cord mesenchymal stem cells secrete β‐NGF, which binds to the TrkA receptor on neurons, upregulates the protein levels of STMN2 and NMNAT2 in mice with perioperative neurocognitive disorders, and thereby downregulates the protein levels of SARM1 and p‐NF‐κB.
Kai Wang   +9 more
wiley   +1 more source

Alterations of the amygdala in post-COVID olfactory dysfunction. [PDF]

open access: yesSci Rep
Thaploo D   +19 more
europepmc   +1 more source

Exosomal TGM2 From Hypoxia‐Primed Olfactory Mucosa MSCs Attenuates Senescent Astrocytes via NRF1/TFAM Signaling in Parkinson's Disease

open access: yesComprehensive Physiology, Volume 16, Issue 4, August 2026.
Hypoxia‐preconditioned olfactory mucosa mesenchymal stem cells (OM‐MSCs) release exosomes enriched with transglutaminase 2 (TGM2), which are taken up by astrocytes. Inside the nucleus, TGM2 activates NRF1, leading to the upregulation of TFAM. This enhances mitochondrial function by reducing mitochondrial DNA (mtDNA) leakage and improving mitochondrial ...
Xiqi Hu   +7 more
wiley   +1 more source

Yin Yang 1 Specifically Supports the Development of Olig2 Positive Cerebellar Astrocytes

open access: yesGlia, Volume 74, Issue 8, August 2026.
Cerebellar Olig2 positive astrocytes are most abundant in the cerebellar nuclei. Cerebellar astrocytes expressing Olig2 have unique gene expression profiles. Yin Yang 1 specifically supports the development of astrocytes expressing Olig2. Deletion of YY1 during development increases numbers of astrocytes expressing Olig2 but hinders their ...
Masoumeh Zarei‐Kheirabadi   +9 more
wiley   +1 more source

Exploring the Paradoxical Association Between Chest CT Pulmonary Involvement and Olfactory Dysfunction in COVID‐19 Patients: A Prospective Cross‐Sectional Study

open access: yesHealth Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Olfactory dysfunction (OD) is common in COVID‐19, yet its relationship with pulmonary involvement remains inconsistent. We evaluated the association between CT‐based lung involvement and OD in laboratory‐confirmed COVID‐19.
Abdolkarim Ghadimi‐Moghadam   +9 more
wiley   +1 more source

Associations between ICU survival and self‐perceived appetite, smell, and taste relative to general ward patients: A prospective study

open access: yesJournal of Parenteral and Enteral Nutrition, Volume 50, Issue 6, Page 805-815, August 2026.
Abstract Background Post‐intensive care unit (ICU) patients frequently fail to meet nutritional requirements during recovery on the hospital ward. Alterations in appetite, smell and taste perception in ICU survivors remain poorly understood. This study compared appetite and sensory perceptions between ICU survivors and general ward patients and ...
Max Melchers   +4 more
wiley   +1 more source

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