Results 41 to 50 of about 93,027 (303)
Potential antidepressant effects of scutellaria baicalensis, hericium erinaceus and rhodiola rosea [PDF]
, 2020 Recent studies focused on the pharmacology and feasibility of herbal compounds as a potential strategy to target a variety of human diseases ranging from metabolic to brain disorders. Accordingly, bioactive ingredients which are found within a variety of
Biagioni, F +5 more
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Histological markers in nasal mucosa of patients with Alzheimer's disease [PDF]
, 1998 Neuropathological changes such as dystrophic neurites and the presence of abnormal tau protein in the olfactory system, including primary sensory cells and nerve fibres have previously been demonstrated in nasal mucosa tissue of patients with Alzheimer's
Golombowski, Sidonie +7 more
core +1 more source
Olfactory Evaluation in Alzheimer’s Disease Model Mice
Brain Sciences, 2022 Olfactory dysfunction is considered a pre-cognitive biomarker of Alzheimer’s disease (AD). Because the olfactory system is highly conserved across species, mouse models corresponding to various AD etiologies have been bred and used in numerous studies on
Jingjing Zhang +10 more
doaj +1 more source
PLoS ONE, 2023 BackgroundOlfactory dysfunction is a common manifestation in COVID-19 patients and can significantly impact their quality of life. Corticosteroids have been proposed as a potential treatment, but their efficacy remains controversial.
Jian-Ying Wang +5 more
doaj +1 more source
Enhanced self-administration of the CB1 receptor agonist WIN55,212-2 in olfactory bulbectomized rats: evaluation of possible serotonergic and dopaminergic underlying mechanisms [PDF]
, 2014 Depression has been associated with drug consumption, including heavy or problematic cannabis use. According to an animal model of depression and substance use disorder comorbidity, we combined the olfactory bulbectomy (OBX) model of depression with ...
Amchova P +11 more
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Olfactory dysfunction in dementia
World Journal of Clinical Cases, 2014 The natural aging process brings about some inevitable consequences, such as olfactory dysfunction, which is also frequently linked to numerous neurodegenerative disorders. Many age-related dementia, such as Alzheimer's disease, Vascular dementia, Parkinson's disease, and Frontotemporal Dementia often display olfactory dysfunction.
Jorge, Alves +2 more
openaire +2 more sources
Olfactory dysfunction and its related molecular mechanisms in Parkinson’s disease
Neural Regeneration ResearchChanges in olfactory function are considered to be early biomarkers of Parkinson’s disease. Olfactory dysfunction is one of the earliest non-motor features of Parkinson’s disease, appearing in about 90% of patients with early-stage Parkinson’s disease ...
Yingying Gu +6 more
doaj +1 more source
Olfactory Dysfunction in Familial and Sporadic Parkinson's Disease
Frontiers in Neurology, 2020 This minireview discusses our current understanding of the olfactory dysfunction that is frequently observed in sporadic and familial forms of Parkinson's disease and parkinsonian syndromes.
Bruce A. Chase +2 more
doaj +1 more source
Hyposmia and Executive Dysfunction as Predictors of Future Parkinson's Disease: A Prospective Study [PDF]
, 2009 Olfactory deficits and executive dysfunction are early and common symptoms in Parkinson's disease (PD). Previous studies have shown that hyposmia can be a first sign of PD.
Berendse +27 more
core +3 more sources
Olfactory Dysfunction and Glaucoma
BiomedicinesBackground: Olfactory dysfunction is a well-known phenomenon in neurological diseases with anosmia and hyposmia serving as clinical or preclinical indicators of Alzheimer’s disease, Parkinson’s disease, and other neurodegenerative disorders. Since glaucoma is a neurodegenerative disease of the visual system, it may also entail alterations in olfactory ...
Iannucci Valeria +7 more
openaire +4 more sources