Results 81 to 90 of about 653,353 (249)

Prevalence of olfactory dysfunction according to tinnitus and analyzed factors.

, 2018
Prevalence of olfactory dysfunction according to tinnitus and analyzed factors.
Jae Yong Lee (1854661), Chang-Hoon Kim (491637), Hyun Jun Kim (5056640), Ji Ho Choi (782575), Kyungdo Han (507253), Do-Yang Park (5884007)   +5 more
core   +1 more source

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism

Advanced Science, EarlyView.
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
Yuchen He, Yuwen Wang, Jonathan F. Gong, Yiting Lei, Fei Jin, Weihong Zhu, Rocky S. Tuan, Zhong Alan Li   +7 more
wiley   +1 more source

Analysis of risk factors affecting olfactory dysfunction in patients with chronic rhinosinusitis: Highlighting the role of metabolic syndrome

Laryngoscope Investigative Otolaryngology, 2023
Objective This study aims to evaluate the relationship between chronic sinusitis (CRS) and metabolic syndrome (MS) in a Chinese population and to explore the risk factors for olfactory dysfunction in patients with CRS. Methods A total of 387 CRS patients
Ling Zhang, Tao Wang, Zhu Wang, Haifeng Li, Yang Wu, Siquan Guo, Wenjing Li, Jianqiang You, Changjiang Chao   +8 more
doaj   +1 more source

Restores Aβ Clearance by Overcoming PCSK9–LRP1 Dysregulation and TRIB3‐Mediated Autophagy Blockade in Alzheimer's Disease

Advanced Science, EarlyView.
PCSK9 upregulation in cerebrovascular endothelial cells and microglia destabilizes the Aβ transporter LRP1, while TRIB3‐associated autophagy blockade further limits intracellular Aβ degradation. A RAP‐modified tea‐polyphenol nanoparticle co‐delivers siPCSK9 and siTRIB3 to restore LRP1‐mediated Aβ efflux and autophagy‐dependent degradation, reducing Aβ ...
Jie Miao, Jing Wang, Yankun Li, Haipei Zhang, Yanli Zhang, Qingnian Li, Bo Xiao, Wenhu Zhou, Junhong Guo   +8 more
wiley   +1 more source

Prevalence and Outcome of Olfactory Dysfunction in COVID-19 Patients in a Multiracial Asian Setting

B-ENT, 2022
Objective: This study aimed to outline the prevalence and the outcome of olfactory dysfunction in a multiracial Asian setting. Methods: The olfactory function of adult patients (above 18 years of age) who tested positive for coronavirus disease 2019 via ...
Jeyasakthy Saniasiaya, Nurul Asma Che Ab Rahim, Carren Sui-Lin Teh, Narayanan Prepageran   +3 more
doaj   +2 more sources

Olfactory Dysfunction. [Elektronisk resurs]

, 2013
Olfactory dysfunction is well documented as an early nonmotor manifestation of Parkinson’s disease (PD). This chapter outlines the anatomy and physiology of the olfactory system and summarizes the pathological changes in the olfactory system in PD.
Wszolek, Zbigniew K., Lund University., Puschmann, Andreas,   +2 more
core  

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Olfactory dysfunction revisited: a reappraisal of work-related olfactory dysfunction caused by chemicals

, 2018
Occupational exposure to numerous individual chemicals has been associated with olfactory dysfunction, mainly in individual case descriptions. Comprehensive epidemiological investigations into the olfactotoxic effect of working substances show that the ...
Eberhard Nies, Sabine Werner
core   +1 more source

Olfactory Dysfunction: A Clinical Marker of COVID-19

, 2021
Due to the rapid spread of the SARS-CoV-2 virus, many health systems worldwide are overwhelmed, leading to the triggering of the scarcity of medical resources.
Apar Pokharel
core   +1 more source

SCTR–Expressing Astrocyte–Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac–Foxc2 Epigenetic Axis in an AMPK‐Dependent Manner

Advanced Science, EarlyView.
Astrocytic SCTR modulates depressive‐related phenotypes via AMPKα1, whereas lowered Mt1 blunts Megalin‐dependent AMPKα2 signaling in serotonergic neurons. Diminished AMPKα2 hinders KAT7 nuclear translocation, curtails KAT7 occupancy and H4K8ac at the Foxc2 promoter, and represses Foxc2 transcription, revealing cell‐type‐specific AMPK‐linked epigenetic ...
Fantao Meng, Jing Liu, Juanjuan Dai, Min Wu, Wentao Wang, Mengdi Zhang, Shujun Jiang, Yifan Cao, Lihong Xu, Lin Du, Dan Wang, Di Zhao, Gaofeng Qin, Dong Wang, Wei Li, Chen Li   +15 more
wiley   +1 more source