Results 281 to 290 of about 125,273 (334)

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Olfactory cleft biopsy analysis of Alzheimer's disease pathobiology across disease stages. [PDF]

Nat Commun
D'Anniballe VM, Kim S, Finlay JB, Wang M, Ko T, Luo S, Whitson HE, Johnson KG, Goldstein BJ.   +8 more
europepmc   +1 more source

Variability in intracellular localization of D‐amino acid oxidase in choroid plexus epithelial cells

The FEBS Journal, EarlyView.
D‐amino acid oxidase (DAO) in choroid plexus epithelial cells (CPECs) shows vesicle‐like localization by histological and super‐resolution analyses. DAO colocalizes with peroxisomal, Golgi, endosomal, lysosomal, autophagosomal, and exosomal markers, indicating diverse subcellular distribution. This suggests DAO is transported within CPECs to metabolize
Koji Ono, Yuji Shishido, Toshiyuki Yamagishi, Kiyoshi Fukui   +3 more
wiley   +1 more source

Mettl3-mediated m6A disruption of olfactory bulb glutamatergic metabolism homeostasis via the Wnt pathway in aging leads to olfactory dysfunction. [PDF]

Cell Mol Life Sci
Hu W, Wang XY, Zhan XJ, Pei P, Kong YR, Ji J, Liu J, Wang S, Tai J.   +8 more
europepmc   +1 more source

The Staircase Chart: Visualising Vertical and Cross‐Shelf Movements and Dispersal of Early‐Life Fish, Applied to Japanese Jack Mackerel

Fisheries Oceanography, EarlyView.
ABSTRACT Dispersal during early life stages is a critical process shaping marine fish connectivity and population dynamics, yet direct field observations at the individual level remain elusive. This has limited our understanding of the factors controlling dispersal, including the impact of active swimming by larvae and juveniles. Here, we present a new
Tatsuya Sakamoto, Daichi Muto, Motomitsu Takahashi, Chiyuki Sassa, Toyoho Ishimura   +4 more
wiley   +1 more source

A review of skin microbiome and new challenges to cosmetic microbiome‐friendly formulations

International Journal of Cosmetic Science, EarlyView.
Microbiome‐friendly concepts offer new perspectives for a healthy relationship between cosmetic use and the skin microbiome, especially the interaction of non‐biotic cosmetic ingredients with the skin, requiring further studies to clarify the dynamics between the skin microbiome and different classes of cosmetic ingredients.
Yasmin Rosa Santos, Newton Andréo‐Filho, Patricia Santos Lopes, Vânia Rodrigues Leite‐Silva   +3 more
wiley   +1 more source

Additional file 6 of Expression atlas of Dmrt genes across sex and development in the mouse brain: functional insights from the olfactory system

Rafael Casado-Navarro, Ana Bermejo-Santos, Rodrigo Torrillas-de la Cal, María Pilar Madrigal, Virgilia Olivé, Li Ying Chen-Chen, Sonia Amorós-Bru, Sandra Jurado, Esther Serrano-Saiz   +8 more
openalex   +1 more source

Genome‐wide and gene‐specific DNA methylation across developmental stages in Pogonomyrmex californicus: A socially polymorphic ant

Insect Molecular Biology, EarlyView.
Comparison between developmental stages (larvae, pupae, worker) in Pogonomyrmex californicus revealed significant stage‐specific differences in Gene Body Methylated frequencies. Methylation sites were highly correlated between WGBS and ONT in P. californicus Genome‐wide methylation was low (~3%) and highly clustered within gene bodies (GBM), especially
Tania Chavarria‐Pizarro, Mohammed Errbii, Janina Rinke, Lukas Schrader, Jürgen Gadau   +4 more
wiley   +1 more source

HP1β and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity. [PDF]

Int J Mol Sci
Escamilla-Del-Arenal M, Duffié R, Shayya H, Loconte V, Ekman A, Street L, Monahan K, Larabell C, Jovanovic M, Lomvardas S.   +9 more
europepmc   +1 more source

Genome and transcriptome‐based identification and expression profiling of chemosensory gene families across developmental stages and tissues in Sirex noctilio (Hymenoptera: Siricidae)

Insect Molecular Biology, EarlyView.
The first draft genome of Sirex noctilio was produced. Fifteen S. noctilio transcriptomes were sequenced to study chemosensory gene expression patterns. SnocOR16 and SnocSNMP1 displayed tissue‐ and sex‐specific expression patterns. Abstract The Sirex woodwasp (Sirex noctilio; Hymenoptera: Siricidae) is among the most destructive invasive pests ...
Alisa Postma, Leandri Klynsmith, Tuan A. Duong, Jeremy Dean Allison, Werner Smidt, Robert M. Waterhouse, Peter Lesny, Jan Philip Oeyen, Malte Petersen, Sebastian Martin, Shanlin Liu, Xin Zhou, Tanja Ziesmann, Alexander Donath, Christoph Mayer, Bernhard Misof, Oliver Niehuis, Ralph S. Peters, Lars Podsiadlowski, Martin P. A. Coetzee, Fourie Joubert, Bernard Slippers   +21 more
wiley   +1 more source