An epigenetic repressor TRIM66 dictates monogenic olfactory receptor expression, neural activity, and olfactory behavior [PDF]
Nature CommunicationsOlfactory receptor gene choice is an intricate example of monogenic and monoallelic expression, where one out of over 1000 receptor genes is transcribed in each olfactory sensory neuron.
Hongqiang Bao +8 more
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Ionotropic crustacean olfactory receptors. [PDF]
PLoS ONE, 2013 The nature of the olfactory receptor in crustaceans, a major group of arthropods, has remained elusive. We report that spiny lobsters, Panulirus argus, express ionotropic receptors (IRs), the insect chemosensory variants of ionotropic glutamate receptors.
Elizabeth A Corey +3 more
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Advantage of the Highly Restricted Odorant Receptor Expression Pattern in Chemosensory Neurons of Drosophila. [PDF]
PLoS ONE, 2013 A fundamental molecular feature of olfactory systems is that individual neurons express only one receptor from a large odorant receptor gene family. While numerous theories have been proposed, the functional significance and evolutionary advantage of ...
Sana Khalid Tharadra +2 more
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Adaptation of olfactory receptor abundances for efficient coding
eLife, 2019 Olfactory receptor usage is highly heterogeneous, with some receptor types being orders of magnitude more abundant than others. We propose an explanation for this striking fact: the receptor distribution is tuned to maximally represent information about ...
Tiberiu Teşileanu +3 more
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Predicting olfactory receptor neuron responses from odorant structure [PDF]
Chemistry Central Journal, 2007 Background Olfactory receptors work at the interface between the chemical world of volatile molecules and the perception of scent in the brain. Their main purpose is to translate chemical space into information that can be processed by neural circuits ...
Hähnel Melanie +3 more
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The Neurotransmitter Receptor Architecture of the Mouse Olfactory System
Frontiers in Neuroanatomy, 2021 The uptake, transmission and processing of sensory olfactory information is modulated by inhibitory and excitatory receptors in the olfactory system. Previous studies have focused on the function of individual receptors in distinct brain areas, but the ...
Kimberley Lothmann +3 more
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Mammalian olfactory receptors [PDF]
Frontiers in Cellular Neuroscience, 2009 Perception of chemical stimuli from the environment is essential to most animals; accordingly, they are equipped with a complex olfactory system capable of receiving a nearly unlimited number of odorous substances and pheromones. This enormous task is accomplished by olfactory sensory neurons (OSNs) arranged in several chemosensory compartments in the ...
Fleischer, Joerg +2 more
openaire +3 more sources
Neuromodulation of olfactory sensitivity in the peripheral olfactory organs of the American cockroach, Periplaneta americana. [PDF]
PLoS ONE, 2013 Olfactory sensitivity exhibits daily fluctuations. Several studies have suggested that the olfactory system in insects is modulated by both biogenic amines and neuropeptides. However, molecular and neural mechanisms underlying olfactory modulation in the
Je Won Jung +5 more
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Profiling of olfactory receptor gene expression in whole human olfactory mucosa. [PDF]
PLoS ONE, 2014 Olfactory perception is mediated by a large array of olfactory receptor genes. The human genome contains 851 olfactory receptor gene loci. More than 50% of the loci are annotated as nonfunctional due to frame-disrupting mutations.
Christophe Verbeurgt +5 more
doaj +1 more source
Tph2-/- female mice restore socio-sexual recognition through upregulating ERα and OTR genes in the amygdala. [PDF]
PLoS ONE, 2018 The central 5-hydroxytryptamine system impairs sociosexual behaviors and olfaction preferences in sexually naive mice. However, it remains unknown whether reproductive experiences impart an effect on the sexual olfactory preferences of female mice ...
Ying Huo +5 more
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