Olfactory Navigation and the Receptor Nonlinearity [PDF]
The demands on a sensory system depend not only on the statistics of its inputs but also on the task. In olfactory navigation, for example, the task is to find the plume source; allocation of sensory resources may therefore be driven by aspects of the plume that are informative about source location, rather than concentration per se.
Jonathan D. Victor +5 more
openaire +2 more sources
Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini +28 more
wiley +1 more source
Gain Control and Sparse Representations in the Olfactory System of the Locust and Fly [PDF]
The giant GABAergic neuron (GGN) is a single, paired, non-spiking neuron that arborizes extensively in the mushroom body (MB) of the locust (Leitch and Laurent, 1996), where it overlaps with the dendrites and the axons of Kenyon cells (KCs).
Papadopoulou, Maria
core +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
Optophysiological analysis of pattern classification strategies in the zebrafish olfactory bulb [PDF]
Classification of overlapping activity patterns is a common problem for sensory systems. For a robust representation of sensory stimuli, neuronal circuits should generalize over input patterns reflecting variations of the same stimulus but separate ...
Niessing, Jörn
core +1 more source
Homozygous deletion of six olfactory receptor genes in a subset of individuals with Beta-thalassemia. [PDF]
Progress in the functional studies of human olfactory receptors has been largely hampered by the lack of a reliable experimental model system. Although transgenic approaches in mice could characterize the function of individual olfactory receptors, the ...
Jessica Van Ziffle +2 more
doaj +1 more source
Memory and Resting‐State Connectivity in Acute Transient Global Amnesia: A Case–Control fMRI Study
ABSTRACT Background and Objectives Transient global amnesia (TGA) is a striking model of isolated amnesia. While hippocampal lesions are well described, the network‐level mechanisms and the precise neuropsychological profile remain debated. Our objective was thus to characterize functional and neuropsychological correlates of acute TGA and their ...
Elias El Otmani +10 more
wiley +1 more source
A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi +17 more
wiley +1 more source
Reconstruction of neuronal activity and connectivity patterns in the zebrafish olfactory bulb [PDF]
In the olfactory bulb (OB), odors evoke distributed patterns of activity across glomeruli that are reorganized by networks of interneurons (INs). This reorganization results in multiple computations including a decorrelation of activity patterns across ...
Wanner, Adrian A.
core +1 more source
Odorant receptor co-receptors affect expression of tuning receptors in Drosophila
Insects detect odorants using two large families of heteromeric receptors, the Odorant Receptors (ORs) and Ionotropic Receptors (IRs). Most OR and IR genes encode odorant-binding “tuning” subunits, whereas four (Orco, Ir8a, Ir25a, and Ir76b) encode co ...
Teng Long +5 more
doaj +1 more source

