Results 61 to 70 of about 90,330 (310)

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

Advanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj, Roshni Satheesh Babu, Yuxin Xia, Eva Bestelink, Radu Sporea, Nikos Hastas, Ioannis Zeimpekis, Dimitra G. Georgiadou, Sayani Majumdar   +8 more
wiley   +1 more source

Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex [PDF]

, 2008
Smoking behavior has been associated in two independent European cohorts with the most common Caucasian human leukocyte antigen (HLA) haplotype (A1-B8-DR3). We aimed to test whether polymorphic members of the two odorant receptor (OR) clusters within the
Yu CY, Volz A, Ziegler, Andreas, Horton, Roger, Uchanska-Ziegler, Barbara, Ziegler A, Sandro Carvalho Santos, P., Füst, George, Miretti, M., Santos, Pablo Sandro Carvalho, Miretti, Marcos Mateo, Yu, Chack-Yung, Uchanska-Ziegler, B., Prohászka, Z., Yu, C.-Y., Horton, R., Beck S, Volz, A., Beck, Stephan G., Miretti M, Beck, S., Volz, Armin, Prohászka, Zoltán, Santos PSC, Füst, György, Füst, G., Uchanska-Ziegler B, Ziegler, A., Horton R   +28 more
core   +1 more source

Monoallelic Expression of Olfactory Receptors [PDF]

Annual Review of Cell and Developmental Biology, 2015
The sense of smell collects vital information about the environment by detecting a multitude of chemical odorants. Breadth and sensitivity are provided by a huge number of chemosensory receptor proteins, including more than 1,400 olfactory receptors (ORs).
Kevin, Monahan, Stavros, Lomvardas
openaire   +2 more sources

Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs

Advanced Science, EarlyView.
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou, Sisi Luo, Binliang Tang, Zhiqiang Liu, Yuchuan Zhou, Yicong Meng, Zhengmu Wu, Zheng Sun, Weihui Shi, Jianzhong Sheng, Chuanjin Yu, Zhenhua Li, Siyi Wei, Mo Zhang, Yujie Luo, Jing Yan, Xueyun Qin, Jiahang Mo, Chengliang Zhou, Jinsong Li, Hefeng Huang, Yifu Ding, Guolian Ding   +22 more
wiley   +1 more source

A Quantitative Model for Human Olfactory Receptors

, 2012
A wide variety of chemicals having distinct odors are smelled by humans. Odor perception initiates in the nose, where it is detected by a large family of olfactory receptors (ORs).
Sk. Sarif Hassan, Pabitra Pal Choudhury, Aritra Bose   +2 more
core   +1 more source

Novel convolution-based signal processing techniques for an artificial olfactory mucosa [PDF]

, 2009
As our understanding of the human olfactory system has grown, so has our ability to design artificial devices that mimic its functionality, so called electronic noses (e-noses).
Gardner, J. W., Taylor, J. E.
core   +1 more source

Fibronectin1‐Expressing Subicular Circuits Selectively Govern the Retrieval of Novel Object Recognition

Advanced Science, EarlyView.
Fibronectin 1 (FN1)‐expressing subicular subpopulations encode novel object preference and selectively govern retrieval of novel object recognition (NOR) via affecting excitability of entorhinal‐projecting circuit through large conductance Ca2+‐activated potassium (BK) channel. ABSTRACT Novel object recognition (NOR), referring to the cognitive ability
Fan Fei, Jiaying Shi, Jing Xi, Yixiang Xu, Shuye Ying, Xukun Fan, Wangjialu Lu, Zhisheng Li, Menghan Li, Yu Wang, Li Cheng, Lin Yang, Lingyu Xu, Zhong Chen, Cenglin Xu, Yi Wang   +15 more
wiley   +1 more source

Reduced olfactory acuity in recently flightless insects suggests rapid regressive evolution

BMC Ecology and Evolution, 2022
Background Insects have exceptionally fast smelling capabilities, and some can track the temporal structure of odour plumes at rates above 100 Hz. It has been hypothesized that this fast smelling capability is an adaptation for flying.
Stefanie Neupert, Graham A. McCulloch, Brodie J. Foster, Jonathan M. Waters, Paul Szyszka   +4 more
doaj   +1 more source

Evolution of insect olfactory receptors

eLife, 2014
The olfactory sense detects a plethora of behaviorally relevant odor molecules; gene families involved in olfaction exhibit high diversity in different animal phyla. Insects detect volatile molecules using olfactory (OR) or ionotropic receptors (IR) and in some cases gustatory receptors (GRs).
Missbach, Christine, Dweck, Hany K. M., Vogel, Heiko, Vilcinskas, Andreas, Stensmyr, Marcus C., Hansson, Bill S., Grosse-Wilde, Ewald   +6 more
openaire   +6 more sources

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source